The spread of Plasmodium falciparum isolates carrying mutations in the kelch13 (Pfkelch13)
gene associated with artemisinin resistance (PfART-R) in southeast Asia threatens malaria …

The emergence of Plasmodium falciparum resistance to artemisinin in Southeast Asia
threatens malaria control and elimination activities worldwide. Multiple polymorphisms in the …

Background Evidence suggests that the PfKelch13 mutations that confer artemisinin
resistance in falciparum malaria have multiple independent origins across the Greater …

Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification
of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 …

Background Efficacy of artemisinin (ART) agents, a critical element of current malaria control
efforts is threatened by emergence and spread of resistance. Mutations in pfkelch13 gene …

Background The devastating public health impact of malaria has prompted the need for
effective interventions. Malaria control gained traction after the introduction of artemisinin …

Background Partial artemisinin resistance is suspected if delayed parasite clearance (ie,
persistence of parasitaemia on day 3 after treatment initiation) is observed. Validated …

Background Artemisinin resistance mutations in Plasmodium falciparum kelch13 (Pfk13)
have begun to emerge in Africa, with Pfk13-R561H being the first reported in Rwanda in …

Accurate assessment and monitoring of the Plasmodium falciparum Kelch 13 (pfk13) gene
associated with artemisinin resistance is critical to understand the emergence and spread of …

Evolution and spread of malaria parasite Plasmodium falciparum capable of evading
antimalarials are the prime concern to malaria control. The currently effective drug …