Impedance-pH reflux patterns can differentiate non-erosive reflux disease from functional heartburn patients
E Savarino, P Zentilin, R Tutuian, D Pohl… - Journal of …, 2012 - Springer
Introduction Symptom association is important to distinguish non-erosive reflux disease
[NERD; abnormal oesophageal acid exposure time (AET) and/or positive symptom …
[NERD; abnormal oesophageal acid exposure time (AET) and/or positive symptom …
The added value of quantitative analysis of on‐therapy impedance‐pH parameters in distinguishing refractory non‐erosive reflux disease from functional heartburn
M Frazzoni, R Conigliaro, VG Mirante… - …, 2012 - Wiley Online Library
Background By analysis of symptom‐reflux association, endoscopy‐negative refractory
heartburn can be related to acid/non‐acid refluxes with impedance‐pH monitoring …
heartburn can be related to acid/non‐acid refluxes with impedance‐pH monitoring …
The added value of impedance-pH monitoring to Rome III criteria in distinguishing functional heartburn from non-erosive reflux disease
E Savarino, E Marabotto, P Zentilin, M Frazzoni… - Digestive and Liver …, 2011 - Elsevier
INTRODUCTION: Functional heartburn is defined by Rome III criteria as an endoscopy-
negative condition with normal oesophageal acid exposure time, negative symptom …
negative condition with normal oesophageal acid exposure time, negative symptom …
Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease
Introduction: Functional dyspepsia and non-erosive reflux disease (NERD) are prevalent
gastrointestinal conditions with accumulating evidence regarding an overlap between the …
gastrointestinal conditions with accumulating evidence regarding an overlap between the …
Impedance-pH monitoring for diagnosis of reflux disease: new perspectives
M Frazzoni, N De Bortoli, L Frazzoni, S Tolone… - Digestive diseases and …, 2017 - Springer
Heartburn is the most specific symptom of gastroesophageal reflux disease (GERD). In
clinical practice, heartburn relief by a proton pump inhibitor (PPI) trial does suffice to confirm …
clinical practice, heartburn relief by a proton pump inhibitor (PPI) trial does suffice to confirm …
Between GERD and NERD: the relevance of weakly acidic reflux
N de Bortoli, A Ottonello, F Zerbib… - Annals of the New …, 2016 - Wiley Online Library
Nonerosive reflux disease (NERD) is a common condition and the most frequent phenotype
of gastroesophageal reflux disease (GERD). NERD is extremely heterogeneous and …
of gastroesophageal reflux disease (GERD). NERD is extremely heterogeneous and …
Esophageal intraluminal baseline impedance differentiates gastroesophageal reflux disease from functional heartburn
A Kandulski, J Weigt, C Caro, D Jechorek, T Wex… - Clinical …, 2015 - Elsevier
Background & Aims Mucosal integrity can be assessed in patients with gastroesophageal
reflux disease (GERD) by measuring intraluminal baseline impedance (BI). However, it is …
reflux disease (GERD) by measuring intraluminal baseline impedance (BI). However, it is …
Impairment of chemical clearance and mucosal integrity distinguishes hypersensitive esophagus from functional heartburn
M Frazzoni, N de Bortoli, L Frazzoni, M Furnari… - Journal of …, 2017 - Springer
Background Hypersensitive esophagus (HE) is defined by endoscopy-negative heartburn
with a normal acid exposure time but positive symptom association probability (SAP) and/or …
with a normal acid exposure time but positive symptom association probability (SAP) and/or …
Use of pH-impedance testing to evaluate patients with suspected extraesophageal manifestations of gastroesophageal reflux disease
A Malhotra, JW Freston, K Aziz - Journal of clinical …, 2008 - journals.lww.com
Background Although the role of acid reflux in causing atypical GERD symptoms is generally
accepted, the role, if any, of nonacid reflux is controversial, largely because until recently it …
accepted, the role, if any, of nonacid reflux is controversial, largely because until recently it …
Combined multichannel intraluminal impedance and pH esophageal testing compared to pH alone for diagnosing both acid and weakly acidic gastroesophageal …
A Hila, A Agrawal, DO Castell - Clinical Gastroenterology and Hepatology, 2007 - Elsevier
Background & Aims: Twenty-four–hour multichannel intraluminal impedance and pH (MII-
pH) esophageal monitoring detects reflux episodes at all pH levels, including acid reflux and …
pH) esophageal monitoring detects reflux episodes at all pH levels, including acid reflux and …
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