[HTML][HTML] Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study
T Mbangiwa, A Sturny-Leclère, K Lechiile… - The Lancet …, 2024 - thelancet.com
Background HIV-associated cryptococcal meningitis is the second leading cause of AIDS-
related deaths, with a 10-week mortality rate of 25–30%. Fungal load assessed by colony …
related deaths, with a 10-week mortality rate of 25–30%. Fungal load assessed by colony …
[HTML][HTML] Evaluation of trypan blue stain in a haemocytometer for rapid detection of cerebrospinal fluid sterility in HIV patients with cryptococcal meningitis
R Kwizera, A Akampurira, TK Kandole, K Nielsen… - BMC microbiology, 2017 - Springer
Background Quantitative culture is the most common method to determine the fungal burden
and sterility of cerebrospinal fluid (CSF) among persons with cryptococcal meningitis. A …
and sterility of cerebrospinal fluid (CSF) among persons with cryptococcal meningitis. A …
[HTML][HTML] Prospective cohort of AIDS patients screened for cryptococcal antigenaemia, pre-emptively treated and followed in Brazil
MASB Borges, JA de Araújo Filho, BJS Oliveira… - PLoS …, 2019 - journals.plos.org
Background Cryptococcal meningitis has a high morbidity and mortality among AIDS
population. Cryptococcal antigen (CrAg) detection is considered an independent predictor …
population. Cryptococcal antigen (CrAg) detection is considered an independent predictor …
High burden of cryptococcal meningitis among antiretroviral therapy–experienced human immunodeficiency virus–infected patients in Northern Uganda in the era of “ …
M Okwir, A Link, J Rhein, JS Obbo… - Open forum …, 2022 - academic.oup.com
Background The impact of the “test and treat” program for human immunodeficiency virus
(HIV) treatment in rural areas of Uganda on cryptococcal antigen (CrAg) screening or …
(HIV) treatment in rural areas of Uganda on cryptococcal antigen (CrAg) screening or …
Serum cryptococcal antigen titre as a diagnostic tool and a predictor of mortality in HIV‐infected patients with cryptococcal meningitis
J Chen, R Zhang, Y Shen, L Liu, T Qi, Z Wang… - HIV …, 2019 - Wiley Online Library
Objectives The aim was to determine the effectiveness of the serum cryptococcal antigen
(CrAg) test in the diagnosis of concurrent cryptococcal meningitis (CM) and as a predictor of …
(CrAg) test in the diagnosis of concurrent cryptococcal meningitis (CM) and as a predictor of …
[HTML][HTML] Cryptococcal antigenemia is associated with meningitis or death in HIV-infected adults with CD4 100–200 cells/mm3
J Wykowski, SR Galagan, S Govere, CL Wallis… - BMC Infectious …, 2020 - Springer
Abstract Background Cryptococcal antigen (CrAg) screening with fluconazole prophylaxis
has been shown to prevent cryptococcal meningitis and mortality for people living with HIV …
has been shown to prevent cryptococcal meningitis and mortality for people living with HIV …
[HTML][HTML] Point of care testing evaluation of lateral flow immunoassay for diagnosis of cryptococcus meningitis in HIV-positive patients at an urban hospital in Nairobi …
Objectives The objective of this study was to evaluate the performance of lateral flow
immunoassay (LFA) against latex agglutination (LA), India ink and culture in point-of-care …
immunoassay (LFA) against latex agglutination (LA), India ink and culture in point-of-care …
[HTML][HTML] Comparison of cryptococcal antigenemia between antiretroviral naïve and antiretroviral experienced HIV positive patients at two hospitals in Ethiopia
T Beyene, Y Woldeamanuel, D Asrat, G Ayana… - PLoS …, 2013 - journals.plos.org
Background Cryptococcal meningitis is a major cause of HIV/AIDS-related deaths in Africa.
Cryptococcosis is a neglected killer. However, meningitis can be prevented by early …
Cryptococcosis is a neglected killer. However, meningitis can be prevented by early …
Evaluation of screening and treatment of cryptococcal antigenaemia among HIV‐infected persons in S oweto, S outh A frica
NP Govender, M Roy, JF Mendes, TG Zulu… - HIV …, 2015 - Wiley Online Library
Objectives We retrospectively evaluated clinic‐based screening to determine the prevalence
of cryptococcal antigenaemia and management and outcome of patients with antigenaemia …
of cryptococcal antigenaemia and management and outcome of patients with antigenaemia …
Prevalence and sequelae of cryptococcal antigenemia in antiretroviral therapy–experienced populations: an evaluation of reflex cryptococcal antigen screening in …
WJ Hurt, MW Tenforde, M Molefi… - Clinical Infectious …, 2021 - academic.oup.com
Background Evidence to inform cryptococcal antigen (CrAg)–screening guidelines among
ART-experienced populations is lacking. We performed a study evaluating the utility of reflex …
ART-experienced populations is lacking. We performed a study evaluating the utility of reflex …