Osteoporosis is a skeletal disorder characterized by low bone mass and microarchitectural
deterioration of bone tissue with consequent increase in bone fragility and fracture risk …

Osteoporosis is a polygenic disorder and has been demonstrated to be associated with~ 30
candidate genes, the majority of which have also been implicated in the regulation of bone …

Nutritional rickets may be caused by either calcium or vitamin D deficiency. Vitamin D affects
skeletal metabolism indirectly. The association between Vitamin D receptor (VDR) gene …

BACKGROUND: The VDR protein is at the centre of the vitamin D endocrine system, a
complex physiological system with substantial feedback regulatory mechanisms involved in …

Osteoporosis is a common disease with a strong genetic component [1–3], characterized by
reduced bone mass and increased fracture risk. Current evidence suggests that the …

Objective To determine whether vitamin D receptor (VDR) gene start codon polymorphisms
and 3'-end region polymorphisms exerted a combined influence on bone mineral density …

Polymorphyism of the vitamin D receptor (VDR) gene is reported to play a major role in
variations of the genetic regulation of bone mass. The role of VDR polymorphisms within …

Although genetic factors have been strongly implicated in determining bone mineral density
(BMD), the role of the vitamin D receptor (VDR) polymorphism remains controversial. An …

Background: Many studies have reported the association between vitamin D receptor (VDR)
polymorphism and osteoporosis risk. However, their results were conflicting. Six previous …

Background: Type 2 diabetes leads to many microvascular complications, including diabetic
nephropathy, also referred to as diabetic kidney disease. Vitamin D deficiency may play a …