Investigating a dose–response relationship between high-fat diet consumption and the contractile performance of isolated mouse soleus, EDL and diaphragm …

J Hurst, RS James, VM Cox, C Hill, J Tallis - European Journal of Applied …, 2019 - Springer
Purpose Recent evidence has demonstrated an obesity-induced, skeletal muscle-specific
reduction in contractile performance. The extent and magnitude of these changes in relation …

The effect of obesity on the contractile performance of isolated mouse soleus, EDL, and diaphragm muscles

J Tallis, C Hill, RS James, VM Cox… - Journal of Applied …, 2017 - journals.physiology.org
Obesity affects the major metabolic and cellular processes involved in skeletal muscle
contractility. Surprisingly, the effect of obesity on isolated skeletal muscle performance …

Chronic high fat feeding attenuates load‐induced hypertrophy in mice

M Sitnick, SC Bodine, JC Rutledge - The Journal of physiology, 2009 - Wiley Online Library
The incidence of obesity and obesity‐related conditions, such as metabolic syndrome and
insulin resistance, is on the increase. The effect of obesity on skeletal muscle function …

Deleterious effect of high-fat diet on skeletal muscle performance is prevented by high-protein intake in adult rats but not in old rats

E Poggiogalle, F Rossignon, A Carayon… - Frontiers in …, 2022 - frontiersin.org
The phenotype of sarcopenic obesity is frequently associated with impaired muscle strength
and performance. Ectopic lipid deposition may interfere with muscle anabolic response …

The effects of diet composition and chronic obesity on muscle growth and function

LGO de Sousa, AG Marshall… - Journal of Applied …, 2021 - journals.physiology.org
Diet-induced obesity (DIO) is associated with glucose intolerance, insulin resistance (IR),
and an increase in intramyocellular lipids (IMCL), which may lead to disturbances in glucose …

High-fat diet affects measures of skeletal muscle contractile performance in a temperature-specific manner but does not influence regional thermal sensitivity

J Tallis, RS James, ELJ Eyre… - Journal of …, 2022 - journals.biologists.com
The present study examined whether high-fat diet (HFD) consumption for 20 weeks had a
temperature-specific effect on the contractile performance and regional thermal sensitivity of …

Does dietary-induced obesity in old age impair the contractile performance of isolated mouse soleus, extensor digitorum longus and diaphragm skeletal muscles?

C Hill, RS James, VM Cox, J Tallis - Nutrients, 2019 - mdpi.com
Ageing and obesity independently have been shown to significantly impair isolated muscle
contractile properties, though their synergistic effects are poorly understood. We uniquely …

Altered lipid metabolism impairs skeletal muscle force in young rats submitted to a short-term high-fat diet

DE Andrich, Y Ou, L Melbouci… - Frontiers in …, 2018 - frontiersin.org
Obesity and ensuing disorders are increasingly prevalent in young populations. Prolonged
exposure to high-fat diets (HFD) and excessive lipid accumulation were recently suggested …

The impact of obesity on in vivo human skeletal muscle function

NA Maffiuletti, S Ratel, A Sartorio, V Martin - Current Obesity Reports, 2013 - Springer
Despite the considerable efforts that have been made to characterize in vivo human skeletal
muscle function in the last 20 years, there is still controversy about whether obesity affects …

Muscle-specific adaptations, impaired oxidative capacity and maintenance of contractile function characterize diet-induced obese mouse skeletal muscle

KE Shortreed, MP Krause, JH Huang, D Dhanani… - PloS one, 2009 - journals.plos.org
Background The effects of diet-induced obesity on skeletal muscle function are largely
unknown, particularly as it relates to changes in oxidative metabolism and morphology …