Ganciclovir is a nucleoside analogue which is used to treat and prevent cytomegalovirus
(CMV) infection. Most recent clinical studies of ganciclovir in transplant recipients have …

Ganciclovir is a nucleoside guanosine analogue which incorporates ganciclovir
triphosphate (the active moiety) into DNA during elongation, thereby inhibiting viral …

Background: Optimal prophylaxis against cytomegalovirus (CMV) disease for organ
transplant patients at risk for primary infection (donor seropositive, recipient seronegative …

Background. Without effective antiviral prophylaxis, cytomegalovirus (CMV) disease is a
common cause of morbidity and mortality after liver transplantation. In this randomized …

Background. Treatment with prophylactic oral acyclovir, intravenous ganciclovir, or
immunoglobulins to prevent cytomegalovirus (CMV) infection and disease in renal …

Objective: To evaluate the efficacy and safety of ganciclovir for prevention of
cytomegalovirus (CMV) infection and disease. Design: A randomized, placebo-controlled …

Unlike parenteral gancicovir, the efficacy of oral ganciclovir in the prevention and treatment
of cytomegalovirus (CMV) infection in kidney transplantation has not been well documented …

Background. The optimal regimen for the prevention and treatment of cytomegalovirus
(CMV) disease in solid organ transplant recipients remains to be defined, particularly for …

Cytomegalovirus (CMV) disease has had a significant clinical impact on the heart, heart-
lung and lung transplant recipients in our centre. CMV disease has been so severe with …

Synopsis The antiviral nucleoside analogue ganciclovir has demonstrated in vitro activity
against human cytomegalovirus and effectively treats infection caused by this organism in …