Lipotoxicity is characterized by excessive saturated fatty acids in the blood, increasing
storage in non-adipose cells, which leads to changes in the expression pattern of genes …

In obesity, accumulation of lipid in nonadipose tissues, or lipotoxicity, is associated with
endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and ultimately apoptosis. We …

Obesity can have detrimental effects on pregnancy rates in natural conceptions and also in
women undergoing IVF or intracytoplasmic sperm injection (ICSI). This review summarises …

Metabolic disorders such as obesity and type II diabetes in women or negative energy
balance in dairy cows are linked to subfertility. They are associated with lipolysis and …

Mobilization of fatty acids from adipose tissue during metabolic stress increases the amount
of free fatty acids in blood and follicular fluid and is associated with impaired female fertility …

The present study was designed to investigate the effect of diet-induced obesity on
endoplasmic reticulum (ER) stress in oocytes. Swiss albino mice (3 weeks old) were fed with …

A majority of common metabolic diseases can result in excessive lipolysis, leading to
elevated levels of non-esterified fatty acids (NEFAs) in the body fluids. In females, increased …

In the cow a major characteristic of metabolic stress is an elevated level of plasma free fatty
acid, due to increased lipid mobilization from adipose tissue. Elevated levels of free fatty …

Metabolic conditions characterized by elevated free fatty acid concentrations in blood and
follicular fluid are often associated with impaired female fertility. Especially elevated …

The pig oocyte maturation protocol differs from other mammalian species due to
dependence on follicular fluid (FF) supplementation. One of the most abundant components …