Sepsis is a complex clinical syndrome characterized by a systemic inflammatory response to
an infective insult. This process often leads to widespread tissue injury and multiple organ …

Sepsis is a serious medical condition that can lead to multi-organ failure and shock, and it is
associated with increased mortality. Acute kidney injury (AKI) is a frequent complication of …

Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …

Sepsis is the most common cause of acute kidney injury (AKI). There has been a growing
body of evidence demonstrating the association between worsening of kidney function …

Although sepsis and acute kidney injury (AKI) have a bidirectional interplay, the
pathophysiological mechanisms between AKI and sepsis are not clarified and worthy of a …

AKI is a common complication of sepsis and is significantly associated with mortality. Sepsis
accounts for more than 50% of the cases of AKI, with a mortality rate of up to 40%. The …

Sepsis is a severe and dysregulated inflammatory response to infection characterized by
end-organ dysfunction distant from the primary site of infection. Development of acute kidney …

Septic acute kidney injury (AKI) occurs between 15% and 20% of all intensive care unit
admissions and its mortality ranges from 20% to 60%. The incidence and mortality of septic …

Given that the leading clinical conditions associated with acute kidney injury (AKI), namely,
sepsis, major surgery, heart failure, and hypovolemia, are all associated with shock, it is …