A Genetic Link to Atrial Substrate in Hypertrophic Cardiomyopathy?

L Dinshaw, C Meyer - Clinical Electrophysiology, 2024 - jacc.org
(HCM) often develop an extensive atrial substrate resulting in persistent atrial fibrillation (AF)
1, 2 and complex atrial tachycardia requiring multiple ablation procedures and …

Atrial fibrillation substrate and catheter ablation outcomes in MYBPC3-and MYH7-mediated hypertrophic cardiomyopathy

IU Haq, N Akhiyat, N Al-Shakarchi, KC Siontis… - JACC: Clinical …, 2024 - Elsevier
Background The effects of disease-causing MYBPC3 or MYH7 genetic variants on atrial
myopathy, atrial fibrillation (AF) clinical course, and catheter ablation efficacy remain …

Impact of genotype on the occurrence of atrial fibrillation in patients with hypertrophic cardiomyopathy

C Bongini, C Ferrantini, F Girolami, R Coppini… - The American journal of …, 2016 - Elsevier
Genes associated with hypertrophic cardiomyopathy (HC) are not uniformly expressed in the
atrial myocardium. Whether this may impact susceptibility to atrial fibrillation (AF) is …

Atrial and ventricular arrhythmias in hypertrophic cardiomyopathy

KR Kumar, SN Mandleywala… - Cardiac …, 2015 - cardiacep.theclinics.com
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by
mutations in genes coding for cardiac sarcomeres. HCM is the most common inherited heart …

[HTML][HTML] Characterization of atrial histology in a patient with hypertrophic cardiomyopathy: possible evidence of a primary atrial myopathy

S Keane, A Fabre, D Keane - HeartRhythm Case Reports, 2021 - Elsevier
Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic myocardial disorder
characterized by primary left ventricular hypertrophy. HCM is the most common inherited …

Genetic determinants of clinical phenotype in hypertrophic cardiomyopathy

L Velicki, DG Jakovljevic, A Preveden… - BMC cardiovascular …, 2020 - Springer
Background Hypertrophic cardiomyopathy (HCM) is the most common inherited
cardiovascular disease that affects approximately one in 500 people. HCM is a recognized …

Atrial fibrillation ablation in patients with hypertrophic cardiomyopathy: do not throw in the towel too fast!

L O'Neill, M Duytschaever, S Knecht - EP Europace, 2021 - academic.oup.com
Current guidelines have emphasized the central role of catheter ablation in the management
of patients with atrial fibrillation (AF). Recent advances in catheter and mapping technology …

[HTML][HTML] Extreme interatrial conduction delay and regularization of atrial arrhythmias in a subgroup of patients with hypertrophic cardiomyopathy

T Szili-Torok, F Akca, K Caliskan, F Ten Cate… - IJC Heart & Vessels, 2014 - Elsevier
Background Hypertrophic cardiomyopathy (HCM) patients may develop interatrial activation
delay, indicated by a complete separation of the right and left atrial activation on the ECG …

Efficacy of catheter ablation for atrial fibrillation in hypertrophic cardiomyopathy: impact of age, atrial remodelling, and disease progression

P Di Donna, I Olivotto, SDL Delcre, D Caponi… - Europace, 2010 - academic.oup.com
Aims In patients with hypertrophic cardiomyopathy (HCM) and atrial fibrillation (AF),
radiofrequency catheter ablation (RFCA) represents a promising option. However, the …

To Screen or Not to Screen, That Is the Question: When to Start Screening Families With Hypertrophic Cardiomyopathy

S Mital, S Ommen - Circulation, 2019 - Am Heart Assoc
A young boy aged 11 years died suddenly while watching his friends play basketball. He
was the third of 4 siblings and had been diagnosed with nonobstructive hypertrophic …