Highly impulsive rats: modelling an endophenotype to determine the neurobiological, genetic and environmental mechanisms of addiction

B Jupp, D Caprioli, JW Dalley - Disease models & …, 2013 - journals.biologists.com
Impulsivity describes the tendency of an individual to act prematurely without foresight and is
associated with a number of neuropsychiatric co-morbidities, including drug addiction. As …

Convergent pharmacological mechanisms in impulsivity and addiction: insights from rodent models

B Jupp, JW Dalley - British journal of pharmacology, 2014 - Wiley Online Library
Research over the last two decades has widely demonstrated that impulsivity, in its various
forms, is antecedent to the development of drug addiction and an important behavioural trait …

[HTML][HTML] Genetic and modeling approaches reveal distinct components of impulsive behavior

KM Nautiyal, MM Wall, S Wang, VM Magalong… - …, 2017 - nature.com
Impulsivity is an endophenotype found in many psychiatric disorders including substance
use disorders, pathological gambling, and attention deficit hyperactivity disorder. Two …

Understanding the construct of impulsivity and its relationship to alcohol use disorders

DM Dick, G Smith, P Olausson, SH Mitchell… - Addiction …, 2010 - Wiley Online Library
There are well‐established links between impulsivity and alcohol use in humans and other
model organisms; however, the etiological nature of these associations remains unclear …

Insight into the relationship between impulsivity and substance abuse from studies using animal models

CA Winstanley, P Olausson, JR Taylor… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Drug use disorders are often accompanied by deficits in the capacity to efficiently process
reward‐related information and to monitor, suppress, or override reward‐controlled behavior …

Found in translation: understanding impulsivity and related constructs through integrative preclinical and clinical research

MN Potenza, JR Taylor - Biological Psychiatry, 2009 - biologicalpsychiatryjournal.com
Addictions are among the most costly disorders, estimated at over $500 billion annually. The
multidimensional construct of impulsivity has received increased attention recently as a …

[HTML][HTML] Special issue on impulsivity and compulsivity

TW Robbins, HV Curran, H De Wit - Psychopharmacology, 2012 - Springer
This 'Special issue on impulsivity and compulsivity'revisits a theme first explored by
Psychopharmacology in 1999 (146, 339–491). That issue of the journal focused on …

[HTML][HTML] The relationship between impulsive choice and impulsive action: a cross-species translational study

N Broos, L Schmaal, J Wiskerke, L Kostelijk, T Lam… - PloS one, 2012 - journals.plos.org
Maladaptive impulsivity is a core symptom in various psychiatric disorders. However, there is
only limited evidence available on whether different measures of impulsivity represent …

Dissecting impulsivity and its relationships to drug addictions

JD Jentsch, JR Ashenhurst… - Annals of the New …, 2014 - Wiley Online Library
Addictions are often characterized as forms of impulsive behavior. That said, it is often noted
that impulsivity is a multidimensional construct, spanning several psychological domains …

Impulsivity in animal models for drug abuse disorders

JD Jentsch - Drug Discovery Today: Disease Models, 2008 - Elsevier
Different conceptual frameworks have been generated to explain substance abuse; of
relevance to this article, dysfunction of impulse control systems that are required for avoiding …