Multiple sclerosis (MS) is a severe disease of the central nervous system (CNS)
characterized by autoimmune inflammation and neurodegeneration. Historically, damage to …

Multiple sclerosis is a chronic debilitating autoimmune disease of the central nervous
system. The contribution of B cells in the pathoetiology of MS has recently been highlighted …

Important antibody-independent pathogenic roles of B cells are emerging in autoimmune
diseases, including multiple sclerosis (MS). The contrasting results of different treatments …

There is ongoing debate on how B cells contribute to the pathogenesis of multiple sclerosis
(MS). The success of B‐cell targeting therapies in MS highlighted the role of B cells …

While it was long held that T cells were the primary mediators of multiple sclerosis (MS)
pathogenesis, the beneficial effects observed in response to treatment with Rituximab (RTX) …

Background: Collectively, research on the role of B-cells in the pathogenesis of multiple
sclerosis (MS) illustrates how translational medicine has given rise to promising therapeutic …

In the last decades, evidence suggesting the direct or indirect involvement of B cells on
multiple sclerosis (MS) pathogenesis has accumulated. The increased amount of data on …

The benefits of therapies targeting B cells in autoimmune diseases have led to increased
interest in the role of B cells in diseases that have been thought to be largely mediated by T …

Background There is increasing evidence that B lymphocytes are involved in the
pathogenesis of multiple sclerosis, and they may be a therapeutic target. Rituximab, a …

Increasing evidence has suggested that both antibody-dependent and antibody-
independent functions of B cells are involved in multiple sclerosis (MS). The contrasting …