Effects of vascular endothelial growth factor in ischemic stroke

Y Ma, A Zechariah, Y Qu… - Journal of neuroscience …, 2012 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a pleiotropic growth factor that is crucially
involved in neurovascular remodeling in the ischemic brain. VEGF promotes angiogenesis …

Implications of vascular endothelial growth factor for postischemic neurovascular remodeling

DM Hermann, A Zechariah - Journal of Cerebral Blood Flow …, 2009 - journals.sagepub.com
Neurovascular remodeling has been recently recognized as a promising target for
neurologic therapies. Hopes have emerged that, by stimulating vessel growth, it may be …

Vascular endothelial growth factor in cerebral ischemia

Y Ma, Y Qu, Z Fei - Journal of neuroscience research, 2011 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is involved in many central nervous system
disorders, including stroke, and confers neuroprotection in cerebral ischemia. In this Mini …

Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis

PS Manoonkitiwongsa, RL Schultz… - Journal of Cerebral …, 2004 - journals.sagepub.com
Vascular endothelial growth factor (VEGF) is currently considered a potential pharmacologic
agent for stroke therapy because of its strong neuroprotective and angiogenic capacities …

[HTML][HTML] VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

Y Sun, K Jin, L Xie, J Childs, XO Mao… - The Journal of …, 2003 - Am Soc Clin Investig
Vascular endothelial growth factor (VEGF) is an angiogenic protein with therapeutic
potential in ischemic disorders, including stroke. VEGF confers neuroprotection and …

[HTML][HTML] Vascular endothelial growth factor augments the tolerance towards cerebral stroke by enhancing neurovascular repair mechanism

A Ghori, V Prinz, M Nieminen-Kehlä, SH Bayerl… - Translational Stroke …, 2022 - Springer
The breakdown of the blood–brain barrier (BBB) is a critical event in the development of
secondary brain injury after stroke. Among the cellular hallmarks in the acute phase after …

Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke

TM Hansen, AJ Moss… - Current Neurovascular …, 2008 - ingentaconnect.com
Vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang1) were originally
identified as endothelial-specific ligands regulating key functions of the vasculature …

[HTML][HTML] Role of vascular endothelial growth factor and other growth factors in post-stroke recovery

T Talwar, MVP Srivastava - Annals of Indian Academy of …, 2014 - journals.lww.com
Stroke is a major health problem world-wide and its burden has been rising in last few
decades. Until now tissue plasminogen activator is only approved treatment for stroke …

[HTML][HTML] Early post-stroke activation of vascular endothelial growth factor receptor 2 hinders the receptor 1-dependent neuroprotection afforded by the endogenous …

A Cárdenas-Rivera, AN Campero-Romero… - Frontiers in Cellular …, 2019 - frontiersin.org
Vascular endothelial growth factor (VEGF) has long been connected to the development of
tissue lesion following ischemic stroke. Contradictory findings either situate VEGF as a …

Vascular endothelial growth factor isoform-B stimulates neurovascular repair after ischemic stroke by promoting the function of pericytes via vascular endothelial …

N Jean LeBlanc, R Guruswamy, A ElAli - Molecular Neurobiology, 2018 - Springer
Ischemic stroke triggers endogenous angiogenic mechanisms, which correlates with longer
survival in patients. As such, promoting angiogenesis appears to be a promising approach …