Immediate-type drug hypersensitivity is an increasingly significant clinical issue; however,
the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow …

Background The flow cytometric basophil activation test by detection of CD63 expression
has been developed as an alternative method for in vitro diagnosis of IgE‐mediated …

The flow cytometric basophil activation test (BAT), based on the detection of allergen-
induced CD63 expression, has been proved effective in the diagnosis of various IgE …

Physicians predominantly rely upon quantification of serum‐specific immunoglobulin E (IgE)
and/or skin test to confirm clinically suspected IgE‐mediated allergy. However, for various …

In most patients, controlled oral food challenges remain the gold standard in the diagnostic
work-up of suspected food allergy. The skin prick test and measurement of specific IgE …

Background Peanut and tree nut allergies are the most important causes of anaphylaxis. Co‐
reactivity to more than one nut is frequent, and co‐sensitization in the absence of clinical …

■ Abstract The standard of reporting in diagnostic studies has generally been low.
Fortunately, this issue has begun to be addressed in recent years through the discussion of …

Background The prevalence of sesame food allergy (SFA) has increased over recent years,
with the potential of anaphylactic reactions upon exposure. Oral food challenge (OFC) …

Abstract The European Academy of Allergy and Clinical Immunology (EAACI) is updating
the Guidelines on Food Allergy Diagnosis. We aimed to undertake a systematic review of the …

The diagnosis of food allergy can have a major impact on the lives of patients and families,
imposing dietary restrictions and limitations on social activities. On the other hand …