TNF-α and-β gene polymorphisms in multiple sclerosis: a highly significant role for determinants in the first intron of the TNF-β gene
JAM Fernandes Filho, CA Vedeler, KM Myhr… - …, 2002 - Taylor & Francis
Tumor necrosis factor (TNF)-f and TNF-g are proinflammatory cytokines that have been
implicated in the pathogenesis of several autoimmune diseases. The aim of this …
implicated in the pathogenesis of several autoimmune diseases. The aim of this …
The polymorphisms of the TNF-α gene in multiple sclerosis?—a meta-analysis
L Xu, W Yuan, H Sun, X Zhang, X Jia, C Shen… - Molecular biology …, 2011 - Springer
The association between multiple sclerosis (MS) and tumor necrosis factor-alpha gene (TNF-
α) polymorphisms has been analyzed in several studies, but conflicting results have been …
α) polymorphisms has been analyzed in several studies, but conflicting results have been …
TNF‐α promoter polymorphisms in multiple sclerosis: no association with− 308 and− 238 alleles, but the− 857 alleles in associated with the disease in Turkish patients
Dysregulation in the expression of pro‐and anti‐inflammatory cytokines is one of the
milestones in multiple sclerosis (MS) development and progression. Tumour necrosis factor …
milestones in multiple sclerosis (MS) development and progression. Tumour necrosis factor …
TNF-α promoter polymorphisms, production and susceptibility to multiple sclerosis in different groups of patients
TWJ Huizinga, RGJ Westendorp, ELEM Bollen… - Journal of …, 1997 - Elsevier
TNF-α production in whole blood cultures upon stimulation with LPS was determined in 179
individuals from 61 families in order to characterise the magnitude of inherited differences in …
individuals from 61 families in order to characterise the magnitude of inherited differences in …
Gene polymorphism at position–308 of the tumor necrosis factor α promotor is not associated with disease progression in multiple sclerosis patients
M Mäurer, N Kruse, R Giess, K Kyriallis, KV Toyka… - Journal of …, 1999 - Springer
Tumor necrosis factor-α (TNFα) is a pluripotent proinflammatory cytokine and is thought to
play an important role in the inflammatory process of multiple sclerosis (MS). AG→ A …
play an important role in the inflammatory process of multiple sclerosis (MS). AG→ A …
TNF-α and TNF-β gene polymorphisms in systemic sclerosis
JP Pandey, F Takeuchi - Human immunology, 1999 - Elsevier
Tumor necrosis factor (TNF)-α and TNF-β, mediators of inflammatory responses, have been
implicated in the pathogenesis of autoimmune diseases. The aim of this investigation was to …
implicated in the pathogenesis of autoimmune diseases. The aim of this investigation was to …
Association of TNFAIP3 and TNFRSF1A variation with multiple sclerosis in a German case–control cohort
S Hoffjan, A Okur, JT Epplen… - International journal …, 2015 - Wiley Online Library
Variations in two genes of the tumour necrosis factor (TNF) alpha pathway have been
implicated in the pathogenesis of autoimmune diseases: polymorphisms in the TNFRSF 1A …
implicated in the pathogenesis of autoimmune diseases: polymorphisms in the TNFRSF 1A …
Genetic variants in the tumor necrosis factor receptor II gene in patients with multiple sclerosis
R Ehling, C Gassner, A Lutterotti… - Tissue …, 2004 - Wiley Online Library
Common genetic variants have been shown to influence disease susceptibility, disease
course, or both in multiple sclerosis (MS). Several studies have suggested a role for tumor …
course, or both in multiple sclerosis (MS). Several studies have suggested a role for tumor …
A population-based case-control study of the tumor necrosis factor alpha-308 polymorphism in multiple sclerosis
D Wingerchuk, Q Liu, J Sobell, S Sommer… - Neurology, 1997 - AAN Enterprises
Tumor necrosis factor alpha (TNFα) expression in enhanced in patients with active MS and
other inflammatory disease. A guanine-to-adenine polymorphism at position-308 of the …
other inflammatory disease. A guanine-to-adenine polymorphism at position-308 of the …
Decreased frequency of the tumor necrosis factor α–308 allele in Serbian patients with multiple sclerosis
J Drulović, D Popadić, Š Mesaroš, I Dujmović… - European …, 2003 - karger.com
Tumor necrosis factor (TNF) α has been considered the prototypic cytopathogenic cytokine
in multiple sclerosis (MS), but recently this cytokine has been shown to possess significant …
in multiple sclerosis (MS), but recently this cytokine has been shown to possess significant …
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