Metabolomic characterization of myocardial ischemia-reperfusion injury in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary …

A Surendran, M Aliani, A Ravandi - Scientific reports, 2019 - nature.com
Aim: The aim of the study was to discover the metabolomic changes in plasma that occur
during human Ischemia-Reperfusion (I/R) injury and to evaluate the diagnostic utility of …

Proteomic and metabolomic characterization of cardiac tissue in acute myocardial ischemia injury rats

H Bai, K Sun, JH Wu, ZH Zhong, SL Xu, HR Zhang… - PLoS …, 2020 - journals.plos.org
The pathological process and mechanism of myocardial ischemia (MI) is very complicated,
and remains unclear. An integrated proteomic-metabolomics analysis was applied to …

Abnormal fatty acid metabolism and ceramide expression may discriminate myocardial infarction from strangulation death: A pilot study

SJ Wang, BR Liu, F Zhang, YP Li, XR Su, CT Yang… - Tissue and Cell, 2023 - Elsevier
Determining myocardial infarction (MI) and mechanical asphyxia (MA) was one of the most
challenging tasks in forensic practice. The present study aimed to investigate the potential of …

The amino acid metabolomics signature of differentiating myocardial infarction from strangulation death in mice models

SJ Wang, BR Liu, F Zhang, XR Su, YP Li, CT Yang… - Scientific Reports, 2023 - nature.com
This study differentiates myocardial infarction (MI) and strangulation death (STR) from the
perspective of amino acid metabolism. In this study, MI mice model via subcutaneous …

Effect of acute high-intensity exercise on myocardium metabolic profiles in rat and human study via metabolomics approach

L Wu, J Wang, X Cao, Y Tian, J Li - Scientific Reports, 2022 - nature.com
Acute high-intensity exercise can affect cardiac health by altering substance metabolism.
However, few metabolomics-based studies provide data on the effect of exercise along with …

Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease

Q Zhu, M Qin, Z Wang, Y Wu, X Chen, C Liu, Q Ma… - Cell & bioscience, 2022 - Springer
Background Coronary artery disease (CAD) is a metabolically perturbed pathological
condition. However, the knowledge of metabolic signatures on outcomes of CAD and their …

Untargeted metabolic profiling reveals potential biomarkers in myocardial infarction and its application

H Yao, P Shi, L Zhang, X Fan, Q Shao… - Molecular …, 2010 - pubs.rsc.org
Although some important biomarkers for myocardial injury have been identified, there still
lacks a systematic view of the development and progression of myocardial infarction …

Metabolomics profiling reveals different patterns in an animal model of asphyxial and dysrhythmic cardiac arrest

D Varvarousis, T Xanthos, G Ferino, A Noto… - Scientific Reports, 2017 - nature.com
Cardiac arrest (CA) is not a uniform condition and its pathophysiology strongly depends on
its cause. In this work we have used a metabolomics approach to study the dynamic …

The use of gas chromatography coupled with high-resolution mass spectrometry-based untargeted metabolomics to discover metabolic changes and help in the …

K Zhang, H Yan, R Liu, P Xiang, J Zhang, K Deng… - ACS …, 2021 - ACS Publications
The determination of cause of death (COD) is one of the most important tasks in forensic
practice and is mainly based on macroscopical and microscopical morphological signatures …

Metabolomics study of the biochemical changes in the plasma of myocardial infarction patients

M Zhu, Y Han, Y Zhang, S Zhang, C Wei… - Frontiers in …, 2018 - frontiersin.org
Myocardial infarction (MI) is a common and multifactorial disease that has the highest
morbidity and mortality in the world. Although a number of physiological, pathological, and …