Background This study was performed to identify metabolites associated with incident acute
coronary syndrome (ACS) and explore causality of the associations. Methods and Results …

Coronary heart disease (CHD) is a prevalent and chronic life-threatening disease. However,
there is no reliable way for early diagnosis and prevention of CHD so far. The precise …

Objective To find out the metabolite profile of rats' myocardial tissue of cardiac blood stasis
syndrome (CBSS), and to analyze the metabolic pathway of CBSS rats' myocardial tissue by …

A metabolomic method using reversed-phase liquid chromatography/quadrupole time-of-
flight mass spectrometry (LC-Q-TOF-MS) was developed to obtain a systematic view of the …

Metabonomics/metabolomics is a rapid technology for comprehensive profiling of small
molecule metabolites in cells, tissues, or whole organisms, the application of which has led …

Acute myocardial infarction (AMI) is a leading cause of mortality and morbidity worldwide.
This work aims to investigate the translational potential of a multi-omics study (comprising …

Objective The comprehensive assaying of low-molecular-weight compounds, for example,
metabolomics, provides a unique tool to uncover novel biomarkers and understand …

Aims Current non-invasive diagnostics for acute myocardial infarction (MI) identify
myocardial necrosis rather than the primary cause and therapeutic target—plaque disruption …

In this paper, we describe how we applied LBD techniques to discover lecithin cholesterol
acyltransferase (LCAT) as a druggable target for cardiac arrest. We fully describe our …

Ultra‐performance liquid chromatography/mass spectrometry‐based metabolomics can
been used for discovery of metabolite biomarkers to explore the metabolic pathway of …