Adenosine is known to influence different kinds of cells, including β-cells of the pancreas.
However, the role of this nucleoside in the regulation of insulin secretion is not fully …

Under physiological conditions, insulin secretion from pancreatic β-cells is tightly regulated
by different factors, including nutrients, nervous system, and other hormones. Pancreatic β …

Adenosine A1, A2A, A2B and A3 receptor mRNAs were found to be expressed in mouse
pancreatic islets and Beta-TC6 cells but their physiological or pharmacological actions are …

Mouse islets were used to study the effects of adenosine and its stable analogue L-N6-
phenylisopropyladenosine (L-PIA) on pancreatic beta-cell function. At a high concentration …

Adenosine regulates exocrine and endocrine secretions in the pancreas. Adenosine is
considered to play a role in acini-to-duct signaling in the exocrine pancreas. To identify the …

Previous studies have shown that adenosine, by activation of purinergic A2-receptors,
stimulates glucagon secretion and increases vascular flow rate in isolated perfused …

Adenosine uptake (consisting of both membrane transport and subsequent metabolism) was
studied in mouse pancreatic islets in order to further evaluate the ability of adenosine to …

The pancreatic islets of Langerhans are responsible for the regulated release of the
endocrine hormones insulin and glucagon that participate in the control of glucose …

Adenosine and the synthetic adenosine agonists 2-chloroadenosine and N 6-(L-2-
phenylisopropyl)-adenosine were tested for effects on hormone secretion from the rat …

The effects of adenosine on insulin and glucagon secretions were studied using the isolated
perfused rat pancreas. The secretion of glucagon was stimulated by adenosine at …