[HTML][HTML] Decomposition of overlapping protein complexes: A graph theoretical method for analyzing static and dynamic protein associations
Background Most cellular processes are carried out by multi-protein complexes, groups of
proteins that bind together to perform a specific task. Some proteins form stable complexes …
proteins that bind together to perform a specific task. Some proteins form stable complexes …
[HTML][HTML] Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis
PF Jonsson, T Cavanna, D Zicha, PA Bates - BMC bioinformatics, 2006 - Springer
Background Protein-protein interactions have traditionally been studied on a small scale,
using classical biochemical methods to investigate the proteins of interest. More recently …
using classical biochemical methods to investigate the proteins of interest. More recently …
[HTML][HTML] Detecting overlapping protein complexes based on a generative model with functional and topological properties
Background Identification of protein complexes can help us get a better understanding of
cellular mechanism. With the increasing availability of large-scale protein-protein interaction …
cellular mechanism. With the increasing availability of large-scale protein-protein interaction …
[HTML][HTML] Identifying protein complexes from interaction networks based on clique percolation and distance restriction
Background Identification of protein complexes in large interaction networks is crucial to
understand principles of cellular organization and predict protein functions, which is one of …
understand principles of cellular organization and predict protein functions, which is one of …
Protein complex identification by supervised graph local clustering
Motivation: Protein complexes integrate multiple gene products to coordinate many
biological functions. Given a graph representing pairwise protein interaction data one can …
biological functions. Given a graph representing pairwise protein interaction data one can …
Detecting protein complexes in a PPI network: a gene ontology based multi-objective evolutionary approach
Protein complexes play an important role in cellular mechanism. Identification of protein
complexes in protein–protein interaction (PPI) networks is the first step in understanding the …
complexes in protein–protein interaction (PPI) networks is the first step in understanding the …
Tissue-specific subnetworks and characteristics of publicly available human protein interaction databases
Motivation: Protein-protein interaction (PPI) databases are widely used tools to study cellular
pathways and networks; however, there are several databases available that still do not …
pathways and networks; however, there are several databases available that still do not …