To understand accurate protein dynamics, a highly reproducible proteomics analytical
method is required. The acquired thus knowledge will lead to the diagnosis, treatment and …

The purpose of clinical proteomics is to characterise protein profiles of a plethora of
diseases with the aim of finding specific biomarkers. These are particularly valuable for early …

Nowadays, proteomic studies no longer focus only on identifying as many proteins as
possible in a given sample, but aiming for an accurate quantification of them. Especially in …

Background Proteomics is an analytical technique employed for the identification and
quantitative analysis of total protein content in a cell, tissue or organism using various …

Several metabolic diseases and genetic abnormalities are known to impair the cellular
transcription and translation status and thereby creating a variation in proteome [4], in fact …

Tracing potential biomarkers through proteomics has been further developed and is nearing
realization. The whole sequence of human proteome is becoming better understood with the …

Proteomics is the field of study that includes the analysis of proteins, from either a basic
science prospective or a clinical one. Proteins can be investigated for their abundance …

Liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based proteomics is a
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …

Proteins can provide insights into biological processes at the functional level, so they are
very promising biomarker candidates. The quantification of proteins in biological samples …

Recent advances in proteomics technologies provide tremendous opportunities for
biomarker-related clinical applications; however, the distinctive characteristics of human …