Silencing of GRHL2 induces epithelial‑to‑mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth
N Kawabe, K Matsuoka, K Komeda… - Oncology …, 2023 - spandidos-publications.com
Abstract Grainyhead‑like 2 (GRHL2) is a transcription factor that suppresses epithelial‑to‑
mesenchymal transition (EMT). It has been previously shown that GRHL2 can confer both …
mesenchymal transition (EMT). It has been previously shown that GRHL2 can confer both …
Diverse expression patterns of the EMT suppressor grainyhead‐like 2 (GRHL 2) in normal and tumour tissues
S Riethdorf, S Frey, S Santjer… - … Journal of Cancer, 2016 - Wiley Online Library
The transcription factor grainyhead‐like 2 (GRHL2) plays a crucial role in various
developmental processes. Although GRHL2 recently has attracted considerable interest in …
developmental processes. Although GRHL2 recently has attracted considerable interest in …
[HTML][HTML] GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer
X Pan, R Zhang, C Xie, M Gan, S Yao… - American journal of …, 2017 - ncbi.nlm.nih.gov
The transcription factor, Grainyhead-like 2 (GRHL2), is involved in wound healing,
epidermal integrity, and epithelial-to-mesenchymal transition (EMT) in various biological …
epidermal integrity, and epithelial-to-mesenchymal transition (EMT) in various biological …
EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer
Y He, M Gan, Y Wang, T Huang, J Wang, T Han… - Cell Death & …, 2021 - nature.com
Abstract Grainyhead-like 1 (GRHL1) is a transcription factor involved in embryonic
development. However, little is known about the biological functions of GRHL1 in cancer. In …
development. However, little is known about the biological functions of GRHL1 in cancer. In …
[HTML][HTML] Grainyhead-like 2 promotes tumor growth and is associated with poor prognosis in colorectal cancer
Y Quan, M Xu, P Cui, M Ye, B Zhuang, Z Min - Journal of Cancer, 2015 - ncbi.nlm.nih.gov
GRHL2 was implicated in regulating cancer development. Our previous study demonstrated
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression
Until now the essential transcription factor that determines the epithelial phenotype of breast
cancer has not been identified and its role in epithelial-to-mesenchymal transition (EMT) and …
cancer has not been identified and its role in epithelial-to-mesenchymal transition (EMT) and …
GRHL2 expression functions in breast cancer aggressiveness and could serve as prognostic and diagnostic biomarker for breast cancer
X Bai, Y Li, Y Li, F Li, N Che, C Ni… - Clinical Medicine …, 2022 - journals.sagepub.com
Background: Breast cancer (BC) is the most frequent malignancy in women worldwide and
the leading cause of female cancer–associated death in the world. Grainyhead-like 2 …
the leading cause of female cancer–associated death in the world. Grainyhead-like 2 …
Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma
M Li, Z Li, X Guan, Y Qin - Oncology Letters, 2019 - spandidos-publications.com
Grainyhead like transcription factor 1 (GRHL1) is among the key family genes encoding
transcription factors that serve important roles in inhibiting tumor cell clone growth …
transcription factors that serve important roles in inhibiting tumor cell clone growth …
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer
J Xiang, X Fu, W Ran, Z Wang - Oncogenesis, 2017 - nature.com
Metastasis is one of the typical features of malignancy that significantly increases cancer-
related mortality. Recent studies have shown that epithelial–mesenchymal transition (EMT) …
related mortality. Recent studies have shown that epithelial–mesenchymal transition (EMT) …
Dual role of GRHL3 in bladder carcinogenesis depending on histological subtypes
FC Lammert, J Pannhausen, E Noetzel… - Molecular … - Wiley Online Library
The effect of grainyhead‐like transcription factor 3 (GRHL3) on cancer development
depends on the cancer subtypes as shown in tumor entities such as colorectal or oral …
depends on the cancer subtypes as shown in tumor entities such as colorectal or oral …