Introduction: Current treatment of osteosarcoma includes surgical resection of all gross
disease in conjunction with systemic chemotherapy to control micro-metastatic disease. This …

Osteosarcoma is the most common primary tumor of bone. Approximately 2/3 of patients
who present with localized osteosarcoma can be expected to be cured of their disease with …

Opinion statement Improving cure rates for osteosarcoma continues to be a major challenge.
The clinical management of individual patients is exacting and requires a skilled …

Improving the survival of patients with osteosarcoma has long proved challenging, although
the treatment of this disease is on the precipice of advancement. The increasing feasibility of …

Introduction: In the early seventies chemotherapy significantly improved survival in
osteosarcoma. Since then minor innovations have occurred although recent years have …

Despite significant advancements in the diagnosis and treatment of osteosarcoma to date,
overall survival has remained relatively constant for over 2 decades. The challenge in …

This paper reviews the contribution of chemotherapy in the conquest of osteosarcoma. It
discusses how the treatment of osteosarcoma has evolved over the last five decades …

Osteosarcoma is the bone tumor that most commonly affects children, adolescents, and
young adults. Before 1970, treatment primarily included surgical resection. However, the …

The current management of osteosarcoma (OS) is critically reviewed and a modified
treatment strategy is put forward for discussion. The overall treatment results in high-grade …

Osteosarcoma is the most frequent primary bone tumor and occurs mainly in young patients
(average age: 18 years). No evolution of the survival rates has been recorded for two …