Injectable tissue integrating networks from recombinant polypeptides with tunable order

S Roberts, TS Harmon, JL Schaal, V Miao, K Li… - Nature materials, 2018 - nature.com
Emergent properties of natural biomaterials result from the collective effects of nanoscale
interactions among ordered and disordered domains. Here, using recombinant sequence …

Biomaterials via peptide assembly: Design, characterization, and application in tissue engineering

VP Gray, CD Amelung, IJ Duti, EG Laudermilch… - Acta biomaterialia, 2022 - Elsevier
A core challenge in biomaterials, with both fundamental significance and technological
relevance, concerns the rational design of bioactive microenvironments. Designed properly …

Protein-engineered biomaterials: highly tunable tissue engineering scaffolds

D Sengupta, SC Heilshorn - Tissue Engineering Part B: Reviews, 2010 - liebertpub.com
A common goal in tissue engineering is to attain the ability to tailor specific cell–scaffold
interactions and thereby gain control over cell behavior. The tunable nature of protein …

Order/Disorder in Protein and Peptide‐Based Biomaterials

RV Ulijn, A Lampel - Israel Journal of Chemistry, 2020 - Wiley Online Library
Nature utilizes both order and disorder (or controlled disorder) to achieve exceptional
materials properties and functions, while synthetic supramolecular materials mostly exploit …

Site-selective protein modification: from functionalized proteins to functional biomaterials

JA Shadish, CA DeForest - Matter, 2020 - cell.com
Chemists, biologists, and material scientists alike have long sought to control protein
presentation, orientation, and activity within biomaterials to dictate reaction catalysis …

Biomimetic Structural Proteins: Modular Assembly and High Mechanical Performance

X Zhang, J Li, C Ma, H Zhang, K Liu - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Protein-based biomaterials attract growing interests due to their encoded and
programmable robust mechanical properties, superelasticity, plasticity, shape adaptability …

[PDF][PDF] Peptide‐directed spatial organization of biomolecules in dynamic gradient scaffolds

LW Chow, A Armgarth, JP St‐Pierre… - Advanced healthcare …, 2014 - academia.edu
GAGs through the thickness of the scaffold. Utilizing specific binding peptides to guide
biomolecule concentration and placement mimics the dynamic, biologically relevant …

Self‐assembled proteins and peptides as scaffolds for tissue regeneration

Y Loo, M Goktas, AB Tekinay, MO Guler… - Advanced …, 2015 - Wiley Online Library
Self‐assembling proteins and peptides are increasingly gaining interest for potential use as
scaffolds in tissue engineering applications. They self‐organize from basic building blocks …

Self-assembled peptides: characterisation and in vivo response

DR Nisbet, RJ Williams - Biointerphases, 2012 - pubs.aip.org
The fabrication of tissue engineering scaffolds is a well-established field that has gained
recent prominence for the in vivo repair of a variety of tissue types. Recently, increasing …

Bioactive site-specifically modified proteins for 4D patterning of gel biomaterials

JA Shadish, GM Benuska, CA DeForest - Nature materials, 2019 - nature.com
Protein-modified biomaterials can be used to modulate cellular function in three dimensions.
However, as the dynamic heterogeneous control over complex cell physiology continues to …