Examining the antimicrobial activity and toxicity to animal cells of different types of CO-releasing molecules
LS Nobre, H Jeremias, CC Romão, LM Saraiva - Dalton Transactions, 2016 - pubs.rsc.org
Transition metal carbonyl complexes used as CO-releasing molecules (CORMs) for
biological and therapeutic applications may exhibit interesting antimicrobial activity …
biological and therapeutic applications may exhibit interesting antimicrobial activity …
[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3
HM Southam, TW Smith, RL Lyon, C Liao, CR Trevitt… - Redox biology, 2018 - Elsevier
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
[HTML][HTML] CO-releasing metal carbonyl compounds as antimicrobial agents in the post-antibiotic era
LK Wareham, RK Poole, M Tinajero-Trejo - Journal of Biological Chemistry, 2015 - ASBMB
The possibility of a" post-antibiotic era" in the 21st century, in which common infections may
kill, has prompted research into radically new antimicrobials. CO-releasing molecules …
kill, has prompted research into radically new antimicrobials. CO-releasing molecules …
Synergetic antimicrobial activity and mechanism of clotrimazole-linked CO-releasing molecules
SS Mendes, J Marques, E Mesterházy… - ACS bio & med …, 2022 - ACS Publications
Several metal-based carbon monoxide-releasing molecules (CORMs) are active CO donors
with established antibacterial activity. Among them, CORM conjugates with azole antibiotics …
with established antibacterial activity. Among them, CORM conjugates with azole antibiotics …
A role for reactive oxygen species in the antibacterial properties of carbon monoxide-releasing molecules
AFN Tavares, LS Nobre… - FEMS microbiology letters, 2012 - academic.oup.com
Carbon monoxide-releasing molecules (CO-RMs) are, in general, transition metal carbonyl
complexes that liberate controlled amounts of CO. In animal models, CO-RMs have been …
complexes that liberate controlled amounts of CO. In animal models, CO-RMs have been …
Antimicrobial action of carbon monoxide-releasing compounds
Carbon monoxide (CO) is endogenously produced in the human body, mainly from the
oxidation of heme catalyzed by heme oxygenase (HO) enzymes. The induction of HO and …
oxidation of heme catalyzed by heme oxygenase (HO) enzymes. The induction of HO and …
Recent advances on carbon monoxide releasing molecules for antibacterial applications
J Cheng, J Hu - ChemMedChem, 2021 - Wiley Online Library
Carbon monoxide (CO) has been known as an endogenous signaling molecule in addition
to an air pollutant. It plays a critical role in many physiological and pathological processes …
to an air pollutant. It plays a critical role in many physiological and pathological processes …
Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules
M Desmard, R Foresti, D Morin… - Antioxidants & redox …, 2012 - liebertpub.com
Aims: Carbon monoxide (CO) delivered in a controlled manner to cells and organisms
mediates a variety of pharmacological effects to the extent that CO-releasing molecules (CO …
mediates a variety of pharmacological effects to the extent that CO-releasing molecules (CO …
The Broad-Spectrum Antimicrobial Potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation …
LK Wareham, S McLean, R Begg, N Rana… - Antioxidants & redox …, 2018 - liebertpub.com
Abstract Aims: Carbon monoxide (CO)-releasing molecules (CORMs) are candidates for
animal and antimicrobial therapeutics. We aimed to probe the antimicrobial potential of a …
animal and antimicrobial therapeutics. We aimed to probe the antimicrobial potential of a …
[HTML][HTML] 'Carbon-monoxide-releasing molecule-2 (CORM-2)'is a misnomer: ruthenium toxicity, not CO release, accounts for its antimicrobial effects
HM Southam, MP Williamson, JA Chapman, RL Lyon… - Antioxidants, 2021 - mdpi.com
Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …