Inflammatory pseudotumor of lymph node and spleen: an entity biologically distinct from inflammatory myofibroblastic tumor

JL Kutok, GS Pinkus, DM Dorfman, CDM Fletcher - Human pathology, 2001 - Elsevier
Inflammatory pseudotumors (IPTs) of the lymph node and spleen are an uncommon, benign
cause of lymphadenopathy and/or splenomegaly that often bear striking clinicopathologic …

Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement

CR Antonescu, AJH Suurmeijer, L Zhang… - The American journal …, 2015 - journals.lww.com
Approximately 50% of conventional inflammatory myofibroblastic tumors (IMTs) harbor ALK
gene rearrangement and overexpress ALK. Recently, gene fusions involving other kinases …

Epithelioid inflammatory myofibroblastic sarcoma: an aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear …

A Mariño-Enríquez, WL Wang, A Roy… - The American journal …, 2011 - journals.lww.com
Inflammatory myofibroblastic tumor (IMT) is a mesenchymal neoplasm of intermediate
biological potential, which may recur and rarely metastasize. Pathologic features do not …

ALK, ROS1 and NTRK3 gene rearrangements in inflammatory myofibroblastic tumours

H Yamamoto, A Yoshida, K Taguchi, K Kohashi… - …, 2016 - Wiley Online Library
Aims The aim of this study was to elucidate the pathological features of inflammatory
myofibroblastic tumour (IMT) with gene rearrangement other than ALK. Methods and results …

[HTML][HTML] Expression of ROS1 predicts ROS1 gene rearrangement in inflammatory myofibroblastic tumors

JL Hornick, LM Sholl, P Dal Cin, MA Childress… - Modern Pathology, 2015 - Elsevier
Inflammatory myofibroblastic tumor is a distinctive, rarely metastasizing mesenchymal
neoplasm composed of fascicles of spindle cells with a prominent inflammatory infiltrate …

ALK‐ATIC fusion in urinary bladder inflammatory myofibroblastic tumor

M Debiec‐Rychter, P Marynen… - Genes …, 2003 - Wiley Online Library
In this report, we describe an inflammatory myofibroblastic tumor (IMT) of the urinary bladder
in a 46‐year‐old man. Tumor cells presented striking cytoplasmatic ALK immunopositivity …

ALK-1 expression in inflammatory myofibroblastic tumor of the urinary bladder

T Tsuzuki, C Magi-Galluzzi… - The American journal of …, 2004 - journals.lww.com
Inflammatory myofibroblastic tumor (IMT) of the bladder is an uncommon myofibroblastic
spindle cell proliferation. Because of its cytologic features and infiltrative nature, it may be …

Pulmonary inflammatory myofibroblastic tumor expressing a novel fusion, PPFIBP1–ALK: reappraisal of anti-ALK immunohistochemistry as a tool for novel ALK fusion …

K Takeuchi, M Soda, Y Togashi, E Sugawara… - Clinical Cancer …, 2011 - AACR
Purpose: The anaplastic lymphoma kinase (ALK) inhibitor crizotinib has been used in
patients with lung cancer or inflammatory myofibroblastic tumor (IMT), both types harboring …

Inflammatory myofibroblastic tumor and low-grade myofibroblastic sarcoma: a comparative study of clinicopathologic features and further observations on the …

X Qiu, E Montgomery, B Sun - Human pathology, 2008 - Elsevier
Inflammatory myofibroblastic tumor (IMT) and low-grade myofibroblastic sarcoma (LGMS)
are intermediate-or low-grade malignant myofibroblastic neoplasms. In this study, the …

Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors

Z Tothova, AJ Wagner - Current Opinion in Oncology, 2012 - journals.lww.com
ALK-directed therapy has emerged as a highly effective treatment option for a subset of
patients with IMT and pulmonary adenocarcinoma. A number of additional malignancies …