Less is more: minimal expression of myoendothelial gap junctions optimizes cell–cell communication in virtual arterioles

BO Hald, JCB Jacobsen, SL Sandow… - The Journal of …, 2014 - Wiley Online Library
Key points Electrical signalling in blood vessels is important in acute and long‐term flow
regulation. As myoendothelial gap junctions (MEGJs) provide electrical contacts between …

Signaling across myoendothelial gap junctions—fact or fiction?

C de Wit, M Boettcher, VJ Schmidt - Cell communication & …, 2008 - Taylor & Francis
Gap junctions interconnect vascular cells homocellularly, thereby allowing the spread of
signals along the vessel wall, which serve to coordinate vessel behavior. In addition, gap …

The differential hypothesis: a provocative rationalization of the conducted vasomotor response

CHT Tran, DG Welsh - Microcirculation, 2010 - Wiley Online Library
Microcirculation (2010) 17, 226–236. doi: 10.1111/j. 1549‐8719.2010. 00022. x Abstract
Tissue blood flow is controlled by a branching network of resistance arteries coupled in …

Current perspective on differential communication in small resistance arteries

CHT Tran, DG Welsh - Canadian journal of physiology and …, 2009 - cdnsciencepub.com
Blood flow is controlled by an integrated network of resistance arteries that are coupled in
series and parallel with one another. To dramatically alter tissue perfusion as required …

Myoendothelial contacts, gap junctions, and microdomains: anatomical links to function?

SL Sandow, S Senadheera, PP Bertrand… - …, 2012 - Wiley Online Library
Please cite this paper as: Sandow SL, Senadheera S, Bertrand PP, Murphy TV, Tare M.
Myoendothelial contacts, gap junctions, and microdomains: anatomical links to function …

Intrinsic regulation of microvascular tone by myoendothelial feedback circuits

HAL Lemmey, CJ Garland, KA Dora - Current Topics in Membranes, 2020 - Elsevier
The endothelium is an important regulator of arterial vascular tone, acting to release nitric
oxide (NO) and open Ca 2+-activated K+(K Ca) channels to relax vascular smooth muscle …

Regulation of blood flow in the microcirculation

SS Segal - Microcirculation, 2005 - Taylor & Francis
The regulation of blood flow has rich history of investigation and is exemplified in exercising
skeletal muscle by a concerted interaction between striated muscle fibers and their …

Conceptualizing conduction as a pliant electrical response: Impact of gap junctions and ion channels

BO Hald, DG Welsh - American Journal of Physiology …, 2020 - journals.physiology.org
Vasomotor responses conduct among resistance arteries to coordinate blood flow delivery
pursuant to energetic demand. Conduction is set by the electrical and mechanical properties …

A cell culture model of resistance arteries

LA Biwer, C Lechauve, S Vanhoose, MJ Weiss… - JoVE (Journal of …, 2017 - jove.com
The myoendothelial junction (MEJ), a unique signaling microdomain in small diameter
resistance arteries, exhibits localization of specific proteins and signaling processes that can …

Cell-cell communication in the resistance vasculature: the past, present, and future.

DG Welsh, MS Taylor - Microcirculation, 2012 - search.ebscohost.com
Please cite this paper as: Welsh DG, Taylor MS. Cell-cell communication in the resistance
vasculature: the past, present, and future. Microcirculation 19: 377-378, 2012. Abstract Cell …