A suramin derivative induces enterocyte-like differentiation of human colon cancer cells without lysosomal storage disorder
S Baghdiguian, P Nickel, J Marvaldi, J Fantini - Anti-Cancer Drugs, 1990 - journals.lww.com
Suramin is a polysulfonated naphthylurea currently investigated for the treatment of
advanced malignancy. We have previously reported that suramin was a potent inducer of …
advanced malignancy. We have previously reported that suramin was a potent inducer of …
Short‐term suramin treatment followed by the removal of the drug induces terminal differentiation of HT29‐D4 cells
S Baghdiguian, B Verrier, J Marvaldi… - Journal of cellular …, 1992 - Wiley Online Library
Suramin is an anti‐cancer drug which induces the differentiation of the human colon cancer
clone HT29‐D4. Yet chronic suramin treatment of these cells eventually leads to a marked …
clone HT29‐D4. Yet chronic suramin treatment of these cells eventually leads to a marked …
Double screening of suramin derivatives on human colon cancer cells and on neural cells provides new therapeutic agents with reduced toxicity
S Baghdiguian, P Nickel, J Fantini - Cancer letters, 1991 - Elsevier
Suramin is a polyanionic compound currently used under evaluation for antineoplastic
activity. One of the main problems encountered during clinical trials was an adverse …
activity. One of the main problems encountered during clinical trials was an adverse …
Kinetics of biochemical, electrophysiological and morphological events (including lysosomal disorder) during the course of suramin‐induced differentiation of the …
S Baghdiguian, B Verrier, J Marvaldi… - International journal of …, 1991 - Wiley Online Library
Suramin, a polysulfonated naphtylurea, has been shown to bind to a wide variety of tumor
growth factors, and to exhibit anti‐proliferative effects on several cell lines. We have followed …
growth factors, and to exhibit anti‐proliferative effects on several cell lines. We have followed …
Co-localization of suramin and serum albumin in lysosomes of suramin-treated human colon cancer cells
S Baghdiguian, JA Boudier, JL Boudier, J Fantini - Cancer letters, 1996 - Elsevier
Suramin is a polysulfonated compound currently under investigation for the treatment of
various types of cancer. Pharmacokinetic studies from clinical trials in humans have shown …
various types of cancer. Pharmacokinetic studies from clinical trials in humans have shown …
Evaluation of the effect of suramin on neural cell growth and N-CAM expression
Suramin, a polysulfonated naphthylurea, is currently under investigation for treatment of
advanced malignancy and has been shown to exhibit antiproliferative effects on some cells …
advanced malignancy and has been shown to exhibit antiproliferative effects on some cells …
Effects of suramin on in vitro growth of fresh human tumors
CW Taylor, R Lui, P Fanta… - JNCI: Journal of the …, 1992 - academic.oup.com
Background: Suramin is a polysulfonated urea recently tested in clinical trials as an
anticancer agent. Purpose: To define tumor types for further clinical testing of suramin, we …
anticancer agent. Purpose: To define tumor types for further clinical testing of suramin, we …
The concentration of glucose in the culture medium determines the effect of suramin on the growth and differentiation of the human colonic adenocarcinoma cell clone …
C Rabenandrasana, S Baghdiguian, M Roccabianca… - Cancer letters, 1990 - Elsevier
Suramin, a drug currently used for advanced malignancy, induces the differentiation of the
human colonic adenocarcinoma cell clone HT29-D4 and this process is correlated with a …
human colonic adenocarcinoma cell clone HT29-D4 and this process is correlated with a …
Suramin: prototype of a new generation of antitumor compounds.
RV La Rocca, CA Stein, CE Myers - Cancer Cells (Cold Spring …, 1990 - europepmc.org
Suramin is a polysulfonated compound originally developed nearly 75 years ago for use as
a trypanocidal agent. Recent studies indicate that suramin can also disrupt mammalian cell …
a trypanocidal agent. Recent studies indicate that suramin can also disrupt mammalian cell …
Intracellular localisation of suramin, an anticancer drug, in human colon adenocarcinoma cells: a study by quantitative autoradiography
S Baghdiguian, JL Boudier, JA Boudier… - European Journal of …, 1996 - Elsevier
Suramin is a polysulphonated naphthylurea currently investigated for the treatment of
advanced malignancy. In the present study, we have analysed the uptake and the …
advanced malignancy. In the present study, we have analysed the uptake and the …