The vesicular acetylcholine (ACh) transporter (VAChT) mediates ACh storage by synaptic
vesicles. However, the VAChT-independent release of ACh is believed to be important …

Defining the contribution of acetylcholine to specific behaviors has been challenging, mainly
because of the difficulty in generating suitable animal models of cholinergic dysfunction. We …

An important step for cholinergic transmission involves the vesicular storage of acetylcholine
(ACh), a process mediated by the vesicular acetylcholine transporter (VAChT). In order to …

Acetylcholine, the first chemical to be identified as a neurotransmitter, is packed in synaptic
vesicles by the activity of VAChT (vesicular acetylcholine transporter). A decrease in VAChT …

J. Neurochem.(2010) 113, 943–951. Abstract Mammalian motor nerve terminals contain
hundreds of thousands of synaptic vesicles, but only a fraction of these vesicles is …

A putative vesicular acetylcholine transporter (VAChT) was overexpressed in developing
Xenopus spinal neurons by injection of rat VAChT cDNA or synthetic mRNA into Xenopus …

Cholinergic neurotransmission depends upon the regulated release of acetylcholine. This
requires the loading of acetylcholine into synaptic vesicles by the vesicular acetylcholine …

In vertebrates, nerve muscle communication is mediated by the release of the
neurotransmitter acetylcholine packed inside synaptic vesicles by a specific vesicular …

Efficient cholinergic transmission requires accurate targeting of vesicular acetylcholine
transporter (VAChT) to synaptic vesicles (SVs). However, the signals that regulate this …

The neurotransmitter acetylcholine (ACh) is synthesized by the enzyme choline
acetyltransferase (ChAT) and then transported into synaptic vesicles by the vesicular …