Gallic acid ameliorates colitis by trapping deleterious metabolite ammonia and improving gut microbiota dysbiosis

J Peng, T Liu, P Meng, Y Luo, S Zhu, Y Wang, M Ma… - Mbio, 2024 - Am Soc Microbiol
Gut microbiota dysbiosis is causally related to inflammatory bowel disease (IBD), and
increased levels of the gut metabolite ammonia have been proposed to contribute to IBD …

A holistic view of gallic acid-induced attenuation in colitis based on microbiome-metabolomics analysis

Y Li, Z Xie, T Gao, L Li, Y Chen, D Xiao, W Liu, B Zou… - Food & function, 2019 - pubs.rsc.org
Gallic acid (GA), a plant phenol found in fruits and vegetables, has been recently reported to
attenuate ulcerative colitis (UC). However, the mechanism of GA in UC remains unknown. In …

Impact of gallic acid on gut health: focus on the gut microbiome, immune response, and mechanisms of action

K Yang, L Zhang, P Liao, Z Xiao, F Zhang… - Frontiers in …, 2020 - frontiersin.org
Gallic acid (GA) is a naturally occurring polyphenol compound present in fruits, vegetables,
and herbal medicines. According to previous studies, GA has many biological properties …

Novel gut microbiota patterns involved in the attenuation of dextran sodium sulfate-induced mouse colitis mediated by glycerol monolaurate via inducing anti …

Q Mo, T Liu, A Fu, S Ruan, H Zhong, J Tang, M Zhao… - MBio, 2021 - Am Soc Microbiol
Inflammatory bowel disease (IBD) is a type of immune-mediated chronic and relapsing
inflammatory gastrointestinal symptoms. IBD cannot be completely cured because of the …

N-Acetylglucosamine and its dimer ameliorate inflammation in murine colitis by strengthening the gut barrier function

SI Choi, YC Shin, JS Lee, YC Yoon, JM Kim… - Food & Function, 2023 - pubs.rsc.org
Ulcerative colitis (UC) is a chronic gastrointestinal disease whose incidence is increasing
rapidly worldwide. Anti-inflammatory medications, including 5-aminosalicylic acid (5-ASA) …

Alginate alleviates dextran sulfate sodium-induced colitis by promoting Bifidobacterium animalis and intestinal hyodeoxycholic acid synthesis in mice

Y Pi, X Zhang, Y Wu, Z Wang, Y Bai, X Liu… - Microbiology …, 2022 - Am Soc Microbiol
Alginate (ALG) is known to alleviate intestinal inflammation in inflammatory bowel disease,
but its mechanism of action remains elusive. In the present study, we studied the …

Sodium butyrate alleviates mouse colitis by regulating gut microbiota dysbiosis

X Dou, N Gao, D Yan, A Shan - Animals, 2020 - mdpi.com
Simple Summary Inflammatory bowel disease (IBD) is extremely harmful to animal health
and can affect animal growth and production. Dextran sulfate sodium (DSS) can cause IBD …

Chlorogenic Acid Protects Against Indomethacin-Induced Inflammation and Mucosa Damage by Decreasing Bacteroides-Derived LPS

Y Yan, X Zhou, K Guo, F Zhou, H Yang - Frontiers in immunology, 2020 - frontiersin.org
Background: Chlorogenic acid (CGA), a natural bioactive polyphenol, exerts anti-
inflammatory, antioxidant, and antibacterial effects that support the maintenance of intestinal …

Methyl gallate alleviates acute ulcerative colitis by modulating gut microbiota and inhibiting TLR4/NF-κB pathway

P Zhou, J Lai, Y Li, J Deng, C Zhao, Q Huang… - International Journal of …, 2022 - mdpi.com
Ulcerative colitis (UC) is a complex immune-mediated inflammatory disease. In recent years,
the incidence of UC has increased rapidly, however, its exact etiology and mechanism are …

Gallic acid attenuates murine ulcerative colitis by promoting group 3 innate lymphocytes, affecting gut microbiota, and bile acid metabolism

Y Leng, X Zhang, Q Zhang, J Xia, Y Zhang, C Ma… - The Journal of …, 2024 - Elsevier
Gallic acid (GA), a plant phenol that is widely distributed in fruits and vegetables, and
exhibits a protective role against ulcerative colitis (UC). UC is an inflammatory disease …