Guchang Zhixie Wan protects mice against dextran sulfate sodium-induced colitis through modulating the gut microbiota in colon

Z Wang, Y Liang, J Yu, D Zhang, L Ren, Z Zhang… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Guchang Zhixie Wan (GC) is a traditional
Chinese patent medicine used in the treatment of colitis in clinical trials. Though the notable …

Mannose metabolism normalizes gut homeostasis by blocking the TNF-α-mediated proinflammatory circuit

P Xiao, Z Hu, J Lang, T Pan, RT Mertens… - Cellular & Molecular …, 2023 - nature.com
Mannose is a naturally occurring sugar widely consumed in the daily diet; however,
mechanistic insights into how mannose metabolism affects intestinal inflammation remain …

Ginsenoside CK Alleviates DSS-Induced IBD in Mice by Regulating Tryptophan Metabolism and Activating Aryl Hydrocarbon Receptor via Gut Microbiota Modulation

Y Liu, X Bai, H Wu, Z Duan, C Zhu, R Fu… - Journal of Agricultural …, 2024 - ACS Publications
Dysbiosis of gut microbiota is believed to be associated with inflammatory bowel disease
(IBD). Ginsenoside compound K (CK), the main metabolite of Panax ginseng ginsenoside …

[HTML][HTML] Qingchang Wenzhong decoction accelerates intestinal mucosal healing through modulation of dysregulated gut microbiome, intestinal barrier and immune …

Z Sun, J Li, W Wang, Y Liu, J Liu, H Jiang… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), a group of multifactorial and inflammatory infirmities, is
closely associated with dysregulation of gut microbiota and host metabolome, but effective …

Chlorogenic acid alleviates colon mucosal damage induced by a high‐fat diet via gut microflora adjustment to increase short‐chain fatty acid accumulation in rats

MG Xie, YQ Fei, Y Wang, WY Wang… - Oxidative Medicine and …, 2021 - Wiley Online Library
A high‐fat diet (HFD) has been previously associated with the development of diseases
such as chronic colitis. While chlorogenic acid (CGA) is known to exhibit potent antioxidant …

Fucoidan ameliorated dextran sulfate sodium-induced ulcerative colitis by modulating gut microbiota and bile acid metabolism

X Liu, Y Zhang, W Li, B Zhang, J Yin… - Journal of agricultural …, 2022 - ACS Publications
Gut dysbiosis and bile acid (BA) metabolism disturbance are involved in the pathogenesis of
ulcerative colitis. This study aimed to investigate the effect of fucoidan on BA metabolism …

[HTML][HTML] Unsaturated alginate oligosaccharides (UAOS) protects against dextran sulfate sodium-induced colitis associated with regulation of gut microbiota

N He, Y Yang, H Wang, N Liu, Z Yang, S Li - Journal of Functional Foods, 2021 - Elsevier
Ulcerative colitis (UC) is highly correlated with the perturbation in gut microbiota. In our
previous study, unsaturated alginate oligosaccharides (UAOS), enzymatic degradation …

[HTML][HTML] Gut Protective Effect from Newly Isolated Bacteria as Probiotics against Dextran Sulfate Sodium and Carrageenan-Induced Ulcerative Colitis

Y Ikeda, A Tsuji, S Matsuda - Microorganisms, 2023 - mdpi.com
Gut microbiome dysbiosis might be linked to certain diseases such as inflammatory bowel
diseases (IBDs), which are categorized by vigorous inflammation of the gastrointestinal tract …

Amelioration of colitis by a gut bacterial consortium producing anti-inflammatory secondary bile acids

C Zhou, Y Wang, C Li, Z Xie, L Dai - Microbiology Spectrum, 2023 - Am Soc Microbiol
ABSTRACT The Integrative Human Microbiome Project and other cohort studies have
indicated that inflammatory bowel disease is accompanied by dysbiosis of gut microbiota …

[HTML][HTML] The Cao-Xiang-Wei-Kang formula attenuates the progression of experimental colitis by restoring the homeostasis of the microbiome and suppressing …

W Yu, Q Li, C Shao, Y Zhang, C Kang… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is pathologically characterized by an immune response
accommodative insufficiency and dysbiosis accompanied by persistent epithelial barrier …