Obesity has reached epidemic proportions and is recognised as a significant global health
problem. Increased food intake and decreased physical activity are traditionally to blame for …

In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

Traits related to energy balance and obesity are exceptionally complex, with varying
contributions of genetic susceptibility and interacting environmental factors. The use of …

Aim The obesity epidemic has been largely attributed to changes in lifestyle habits
established over the past three decades. These changes are mainly attributed to excessive …

Obesity is a complex multifaceted disease resulting from interactions between genetics and
lifestyle. The proportion of phenotypic variance ascribed to genetic variance is 0.4 to 0.7 for …

Background Obesity is a global health problem mainly attributed to lifestyle changes such as
diet, low physical activity or socioeconomics factors. However, several evidences …

Multiple biological, behavioural and genetic determinants or correlates of obesity have been
identified to date. Genome-wide association studies (GWAS) have contributed to the …

A substantial proportion of obese individuals do not present cardiometabolic complications
such as diabetes, hypertension, or dyslipidemia. Some, but not all, prospective studies …

Obesity is a global and growing problem. The detrimental health consequences of obesity
are significant and include co-morbidities such as diabetes, cancer and coronary heart …

Obesity is routinely considered as a single disease state, which drives a “one-size-fits-all”
approach to treatment. We recently convened the first annual University of North Carolina …