The epidemic of obesity has become pandemic, putting a significant burden on the world's
healthcare system. While the heritability of the disease is high, all the identified genetic …

The gut microbiota has an extremely important role within the body and it is necessary for
the regulation of the metabolism of the host and also for the development of metabolic …

It is widely accepted that metabolic disorders, such as obesity, are closely linked to lifestyle
and diet. Recently, the central role played by the intestinal microbiota in human metabolism …

Background Genome-wide association studies (GWAS) have recently identified several new
genetic variants associated with obesity. The majority of the variants are within introns or …

Genome-wide association promises to enhance greatly our understanding of the genetic
basis of common obesity, although candidate gene studies will remain a valuable approach …

The increased prevalence of obesity and related comorbidities is a major public health
problem. While genetic factors undoubtedly play a role in determining individual …

The increasing prevalence of obesity worldwide has prompted the World Health
Organization (WHO) to classify it as a global epidemic. Around the globe, more than a half …

Although it appeared relatively suddenly, the current obesity epidemic–largely manifest in
industrialized societies but now spreading to the rest of the world–is the result of interaction …

Mice have proved to be powerful models for understanding obesity in humans and farm
animals. Single-gene mutants and genetically modified mice have been used successfully to …

The past few decades have witnessed a rapid rise in nutrition-related disorders such as
obesity in the United States and over the world. Traditional nutrition research has associated …