[HTML][HTML] Nanoparticles and Airway Epithelial Cells: Exploring the Impacts and Methodologies in Toxicity Assessment

CE Lee, F Rezaee - International Journal of Molecular Sciences, 2024 - mdpi.com
The production of nanoparticles has recently surged due to their varied applications in the
biomedical, pharmaceutical, textile, and electronic sectors. However, this rapid increase in …

Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro

E Chau, JF Galloway, A Nelson, PN Breysse… - …, 2013 - Taylor & Francis
The respiratory system is one of the portals of entry into the body, and hence inhalation of
engineered nanomaterials is an important route of exposure. The broad range of …

A review on toxicity mechanism and risk factors of nanoparticles in respiratory tract

V Khadanga, PC Mishra - Toxicology, 2024 - Elsevier
This comprehensive review focuses on various dimensions of nanoparticle toxicity,
emphasizing toxicological characteristics, assessment techniques, and examinations of …

Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies

E Fröhlich, S Salar-Behzadi - International journal of molecular sciences, 2014 - mdpi.com
The alveolar epithelium of the lung is by far the most permeable epithelial barrier of the
human body. The risk for adverse effects by inhaled nanoparticles (NPs) depends on their …

Nanomaterial interactions with and trafficking across the lung alveolar epithelial barrier: implications for health effects of air-pollution particles

NR Yacobi, F Fazllolahi, YH Kim, A Sipos… - Air Quality, Atmosphere …, 2011 - Springer
Studies on the health effects of air-pollution particles suggest that injury may result from
inhalation of airborne ultrafine particles (< 100 nm in diameter). Engineered nanomaterials …

Toxicity assessment of industrial engineered and airborne process-generated nanoparticles in a 3D human airway epithelial in vitro model

MJ Bessa, F Brandão, P Fokkens, FR Cassee… - …, 2021 - Taylor & Francis
The advanced ceramic technology has been pointed out as a potentially relevant case of
occupational exposure to nanoparticles (NP). Not only when nanoscale powders are being …

Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure

S Ahmad, DO Raemy, JE Loader, JM Kailey… - Journal of aerosol …, 2012 - liebertpub.com
Abstract Background: Nanoparticles (NPs) produced by nanotechnology processes have
taken the field of medicine by storm. Concerns about safety of these NPs in humans …

Pulmonary applications and toxicity of engineered nanoparticles

JW Card, DC Zeldin, JC Bonner… - American Journal of …, 2008 - journals.physiology.org
Because of their unique physicochemical properties, engineered nanoparticles have the
potential to significantly impact respiratory research and medicine by means of improving …

Toxicity and mechanisms of engineered nanoparticles in animals with established allergic asthma

R Deng, Y Zhu, X Wu, M Wang - International Journal of …, 2023 - Taylor & Francis
Asthma is a chronic respiratory disease that is highly sensitive to environmental pollutants,
including engineered nanoparticles (NPs). Exposure to NPs has become a growing concern …

Mechanistic insight into the impact of nanomaterials on asthma and allergic airway disease

K Meldrum, C Guo, EL Marczylo, TW Gant… - Particle and Fibre …, 2017 - Springer
Asthma is a chronic respiratory disease known for its high susceptibility to environmental
exposure. Inadvertent inhalation of engineered or incidental nanomaterials is a concern for …