Molecular mechanisms in endothelial regulation of cardiac function

L Kuruvilla, CC Kartha - Molecular and cellular biochemistry, 2003 - Springer
Endothelium is now recognized as a massive, regionally specific, multifunctional organ.
Given its strategic anatomic location between the circulating blood components and the …

Endothelial control of the cardiovascular system: recent advances

KK Griendling, RW Alexander - The FASEB journal, 1996 - Wiley Online Library
The endothelium is uniquely positioned at the interface between the blood and the vessel
wall. As such, it performs multiple functions: It is involved in the regulation of coagulation …

Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity

DL Brutsaert - Physiological reviews, 2003 - journals.physiology.org
Experimental work during the past 15 years has demonstrated that endothelial cells in the
heart play an obligatory role in regulating and maintaining cardiac function, in particular, at …

The influence of endocardial endothelium on myocardial contraction

JA Smith, AM Shah, S Fort, MJ Lewis - Trends in pharmacological sciences, 1992 - cell.com
A novel unidentified agent, provisionally named 'endocardin', has been shown to be
released from endocardial endothelium. Endocardin has a unique prolonging effect on …

Differences in structure between endocardial and vascular endothelium

LJ Andries, DL Brutsaert - Journal of cardiovascular …, 1991 - journals.lww.com
Knowledge of the functional structure of endocardial endothelium (EE) is required to
understand the mechanisms underlying the recently described modulation of myocardial …

The cardiac endothelium: cardioactive mediators

AM Shah, RM Grocott-Mason, CB Pepper… - Progress in …, 1996 - Elsevier
Endothelial cells within the heart release a number of substances that modulate myocardial
contractile function. These agents include nitric oxide, endothelin, prostanoids …

Cardiac endothelium and myocardial function

DL Brutsaert, P Fransen, LJ Andries… - Cardiovascular …, 1998 - academic.oup.com
Endocardial endothelium and vascular endothelium of myocardial capillaries share common
features as modulators of cardiac performance, rhythmicity and growth. Growing evidence …

[HTML][HTML] Endothelial cell dysfunction in cardiac disease: driver or consequence?

JD Allbritton-King, G García-Cardeña - Frontiers in Cell and …, 2023 - ncbi.nlm.nih.gov
The vascular endothelium is a multifunctional cellular system which directly influences blood
components and cells within the vessel wall in a given tissue. Importantly, this cellular …

Endothelial cell regulation of contractility of the heart

S Winegrad - Annual review of physiology, 1997 - annualreviews.org
▪ Abstract Endocardial and coronary vascular endothelial cells release substances that
modify the contraction of cardiac myocytes. The major and possibly the sole up-regulating …

The endocardial endothelium

DL Brutsaert, LJ Andries - American Journal of Physiology …, 1992 - journals.physiology.org
The heart wall with its complex trabecular structures is covered with a very thin layer of
endocardial endothelial (EE) cells. EE cells appear early during cardiac development; they …