Unlike other normal cells, a subpopulation of cells often termed as “stem cells” are long-lived
and generate cellular progeny throughout life. Cancer stem cells (CSCs) are rare immortal …

Normal somatic stem cells (SC) are naturally resistant to chemotherapeutic agents due to
their expression of various membrane transporter molecules (such as MDR-1), detoxifying …

Over the past two decades cancer stem cells (CSCs) have emerged as essential players in
the pathogenesis of cancer, with the capacity to initiate, maintain and repopulate different …

The study of cancer stem cells (CSCs) has shown that tumors are driven by a subpopulation
of self-renewing CSCs that retain the capacity to engender the various differentiated cell …

Cancer stem cells (CSC) possess abilities generally associated with embryonic or adult
stem cells, especially self-renewal and differentiation. The CSC model assumes that this …

Resistance to tumor therapy is an unsolved problem in cancer treatment. A plethora of
studies have attempted to explain this phenomenon and many mechanisms of resistance …

Cells with stem‐like properties, tumorigenic potential, and treatment‐resistant phenotypes
have been identified in many human malignancies. Based on the properties they share with …

Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that
contribute to tumor progression and therapy resistance. However, the underlying processes …

Despite advances in treatment, cancer remains the 2nd most common cause of death in the
United States. Poor cure rates may result from the ability of cancer to recur and spread after …