Breast cancer is the most frequent cancer among women worldwide. Therapeutic strategies
to prevent or treat metastatic disease are still inadequate although great progress has been …

Cancer metastasis, resistance to therapies and disease recurrence are significant hurdles to
successful treatment of breast cancer. Identifying mechanisms by which cancer spreads …

Breast cancer is marked as one of the leading causes of malignancy-related morbidities
worldwide. In spite of aggressive interventions, the inevitability of relapse and metastasis …

Breast cancer is the leading cause of cancer death among women worldwide. Accumulating
evidence indicates that the local recurrent and/or distant metastatic tumors, the major causes …

Recent studies have identified a small population of highly tumorigenic cells with stem cell
properties in human breast and other solid tumors that are considered to be the source of …

Abstract Development of therapeutic resistance and metastasis is a major challenge with
current breast cancer (BC) therapy. Mounting evidence suggests that a subpopulation of …

Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …

Breast cancer is a heterogeneous disease that accounts for 30% of all cancers diagnosed in
women and over half a million deaths per year. Cancer stem cells (CSCs) make up a small …

Simple Summary Breast cancer stem cells are blamed to be responsible for breast cancer
tumorigenesis, metastasis, drug resistance and tumor recurrence. Therefore, it is critical to …

There is substantial evidence that many cancers, including breast cancer, are driven by a
population of cells that display stem cell properties. These cells, termed cancer stem cells …