Characterizing the role of RNA silencing components in Cryptococcus neoformans

G Janbon, S Maeng, DH Yang, YJ Ko, KW Jung… - Fungal Genetics and …, 2010 - Elsevier
The RNA interference (RNAi) mediated by homology-dependent degradation of the target
mRNA with small RNA molecules plays a key role in controlling transcription and translation …

The transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary …

LS Derengowski, HC Paes, P Albuquerque… - Eukaryotic …, 2013 - Am Soc Microbiol
Virulence of Cryptococcus neoformans for mammals, and in particular its intracellular style,
was proposed to emerge from evolutionary pressures on its natural environment by …

[HTML][HTML] CcpA Coordinates Growth/Damage Balance for Streptococcus pyogenes Pathogenesis

E Paluscio, ME Watson Jr, MG Caparon - Scientific reports, 2018 - nature.com
To achieve maximum fitness, pathogens must balance growth with tissue damage,
coordinating metabolism and virulence factor expression. In the gram-positive bacterium …

Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence

KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …

[HTML][HTML] Noncanonical Gβ Gib2 is a scaffolding protein promoting cAMP signaling through functions of Ras1 and Cac1 proteins in Cryptococcus neoformans

Y Wang, G Shen, J Gong, D Shen, A Whittington… - Journal of Biological …, 2014 - ASBMB
Gβ-like/RACK1 functions as a key mediator of various pathways and contributes to
numerous cellular functions in eukaryotic organisms. In the pathogenic fungus Cryptococcus …

[PDF][PDF] Hypoxia sensing in Cryptococcus neoformans: Biofilm-like adaptation for dormancy

Z Moranova, S Kawamoto, V Raclavsky - Biomed Pap Med Fac Univ …, 2009 - Citeseer
Background: Cryptococcus neoformans is an obligate aerobic pathogenic yeast causing
lung infection typically followed by spread to the central nervous system. During …

Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport

LX Li, CR Hole, J Rangel-Moreno… - Infection and …, 2020 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen that kills almost 200,000 people each year
and is distinguished by abundant and unique surface glycan structures that are rich in …

[HTML][HTML] The multiple regulatory relationship between RNA-chaperone Hfq and the second messenger c-di-GMP

Y Fu, Z Yu, L Zhu, Z Li, W Yin, X Shang… - Frontiers in …, 2021 - frontiersin.org
RNA chaperone protein Hfq is an important post-transcriptional regulator in bacteria, while c-
di-GMP is a second messenger signaling molecule widely distributed in bacteria. Both …

Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment

DL Toffaletti, M Del Poeta, TH Rude… - …, 2003 - microbiologyresearch.org
In the study of differential gene expression of Cryptococcus neoformans, a transcript of
COX1 (cytochrome oxidase c subunit 1) was identified in a serotype A strain. The transcript …

One‐carbon metabolism and microbial pathogenicity

KS Stocke, RJ Lamont - Molecular Oral Microbiology, 2023 - Wiley Online Library
One‐carbon metabolism (OCM) pathways are responsible for several functions, producing a
number of one‐carbon unit intermediates (formyl, methylene, methenyl, methyl) that are …