This chapter discusses the biosynthesis and physiology of nitric oxide (NO) and how both
relate to its unique and fascinating chemistry. It scopes the sheer volume of literature …

A growing appreciation of the involvement of nitric oxide (NO) in numerous bioregulatory
pathways has not only opened up new therapeutic avenues for organic nitrates and other …

Nitric oxide is a highly potent regulatory molecule with great pharmaceutical potential. This
handbook fills a real gap in combining the chemistry of nitric oxide releasing substances …

T he relevance of the nitrogen oxides for clinical medicine has been recognized for over a
century. Nitrous oxide (N, O) has been used safely and effectively for analgesia and …

Publisher Summary This chapter discusses the important aspects of the solution chemistry of
nitrogen oxide (NO) and reactive nitrogen oxide species (RNOS), biochemical targets of NO …

In the body, nitric oxide (NO) is an important physiological regulator of functions such as
vasodilatation and neurotransmission. Under pathological conditions, high concentrations of …

Nitric oxide (NO) plays a pivotal role in the maintenance of cardiovascular homeostasis. A
reduction in the bioavailability of endogenous NO, manifest as a decrease in the production …

Due to the excitement surrounding the discovery of NO as an endogenously generated
signalling molecule, a number of other nitrogen oxides were also investigated as possible …

Simple Summary Nitric oxide is an important molecule that performs a variety of functions in
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …

Compounds formed by reacting nitric oxide (NO) with various nucleophiles have been
shown to dilate aortic segments with a potency that correlates strongly with the amount of …