Outcomes and drivers of inappropriate dosing of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation: a systematic review and meta …

V Caso, JR de Groot, MS Fernandez, T Segura… - Heart, 2023 - heart.bmj.com
Objective There has been limited systematic evaluation of outcomes and drivers of
inappropriate non-vitamin K antagonist oral anticoagulants (NOACs) dosing among patients …

[HTML][HTML] Off-label underdosing or overdosing of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a meta-analysis

X Wu, L Hu, J Liu, Q Gu - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Background: Several studies have investigated the role of off-label non-vitamin K antagonist
oral anticoagulants (NOACs) in patients with atrial fibrillation (AF). We aimed to compare the …

Efficacy and safety of reduced-dose non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a meta-analysis of randomized controlled trials

KL Wang, RD Lopes, MR Patel, HR Büller… - European Heart …, 2019 - academic.oup.com
Aims Non-vitamin K antagonist oral anticoagulants (NOACs) require dose reductions
according to patient or clinical factors for patients with atrial fibrillation (AF). In this meta …

Off‐label underdosing of four individual NOACs in patients with nonvalvular atrial fibrillation: A systematic review and meta‐analysis of observational studies

C Sang, J Chen, J Sun, Y Lai, X Liu… - European Journal of …, 2022 - Wiley Online Library
Background Although several meta‐analyses have examined the effects of off‐label
underdosing of nonvitamin K antagonist oral anticoagulants (NOACs) compared with their …

Off-label dosing of non–vitamin K antagonist oral anticoagulants and clinical outcomes in Asian patients with atrial fibrillation

YH Chan, TF Chao, SW Chen, HF Lee, YH Yeh… - Heart rhythm, 2020 - Elsevier
Background Off-label dosing non–vitamin K antagonist oral anticoagulants (NOACs) are
commonly prescribed for Asian patients with atrial fibrillation (AF). Objective The purpose of …

Label adherence of direct oral anticoagulants dosing and clinical outcomes in patients with atrial fibrillation

HT Yu, PS Yang, E Jang, TH Kim, JS Uhm… - Journal of the …, 2020 - Am Heart Assoc
Background Dose adjustment of non‐vitamin K antagonist oral anticoagulants (NOAC s) is
indicated in some patients with atrial fibrillation (AF), based on selected patient factors or …

Individual patient data from the pivotal randomized controlled trials of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation (COMBINE AF) …

AP Carnicelli, H Hong, RP Giugliano, SJ Connolly… - American Heart …, 2021 - Elsevier
Background Non-vitamin K antagonist oral anticoagulants (NOACs) are the preferred class
of medications for prevention of stroke and systemic embolism in patients with atrial …

Non-vitamin K antagonist oral anticoagulants: impact of non-adherence and discontinuation

JM Rivera-Caravaca, MA Esteve-Pastor… - Expert Opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Non-Vitamin K Antagonist Oral Anticoagulants (NOACs) are at
least as effective as vitamin K antagonists (VKAs) reducing thromboembolism and mortality …

Off-label dosing of non-vitamin K antagonist oral anticoagulants and adverse outcomes: the ORBIT-AF II registry

BA Steinberg, P Shrader, L Thomas, J Ansell… - Journal of the American …, 2016 - jacc.org
Background: Although non-vitamin K antagonist oral anticoagulants (NOACs) do not require
frequent laboratory monitoring, each compound requires dose adjustments on the basis of …

The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation

J Steffel, P Verhamme, TS Potpara… - European heart …, 2018 - academic.oup.com
The current manuscript is the second update of the original Practical Guide, published in
2013 [Heidbuchel et al. European Heart Rhythm Association Practical Guide on the use of …