Immunostimulatory CpG oligonucleotides: Effect on gene expression and utility as vaccine adjuvants
DM Klinman, S Klaschik, K Tomaru, H Shirota, D Tross… - Vaccine, 2010 - Elsevier
Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs mimic the
immunostimulatory activity of bacterial DNA. CpG ODN directly stimulate B cells and …
immunostimulatory activity of bacterial DNA. CpG ODN directly stimulate B cells and …
Adjuvant activity of CpG oligodeoxynucleotides
DM Klinman - International reviews of immunology, 2006 - Taylor & Francis
Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs directly
stimulate human B cells and plasmacytoid dendritic cells (pDCs), thereby promoting the …
stimulate human B cells and plasmacytoid dendritic cells (pDCs), thereby promoting the …
CpG oligonucleotides improve the protective immune response induced by the anthrax vaccination of rhesus macaques
DM Klinman, H Xie, SF Little, D Currie, BE Ivins - Vaccine, 2004 - Elsevier
Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs act as immune
adjuvants, improving the immune response elicited by co-administered vaccines. Combining …
adjuvants, improving the immune response elicited by co-administered vaccines. Combining …
CpG DNA as a vaccine adjuvant
DM Klinman - Expert review of vaccines, 2003 - Taylor & Francis
Synthetic oligodeoxynucleotides containing unmethylated CpG motifs act as immune
adjuvants, accelerating and boosting antigen-specific antibody responses by up to 500-fold …
adjuvants, accelerating and boosting antigen-specific antibody responses by up to 500-fold …
Use of CpG oligodeoxynucleotides as immune adjuvants
DM Klinman, D Currie, I Gursel… - Immunological …, 2004 - Wiley Online Library
Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs directly
stimulate human B cells and plasmacytoid dendritic cells (pDCs), thereby promoting the …
stimulate human B cells and plasmacytoid dendritic cells (pDCs), thereby promoting the …
CpG DNA as a vaccine adjuvant
C Bode, G Zhao, F Steinhagen, T Kinjo… - Expert review of …, 2011 - Taylor & Francis
Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs trigger cells
that express Toll-like receptor 9 (including human plasmacytoid dendritic cells and B cells) …
that express Toll-like receptor 9 (including human plasmacytoid dendritic cells and B cells) …
CpG oligonucleotides accelerate and boost the immune response elicited by AVA, the licensed anthrax vaccine
DM Klinman - Expert review of vaccines, 2006 - Taylor & Francis
Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs act as immune
adjuvants, improving the immune response elicited by coadministered vaccines. Combining …
adjuvants, improving the immune response elicited by coadministered vaccines. Combining …
CpG oligonucleotides improve the protective immune response induced by the licensed anthrax vaccine
DM Klinman, H Xie, BE Ivins - … of the New York Academy of …, 2006 - Wiley Online Library
Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs act as immune
adjuvants, improving the response elicited by a coadministered vaccine. Combining CpG …
adjuvants, improving the response elicited by a coadministered vaccine. Combining CpG …
CpG oligonucleotides as adjuvants for vaccines targeting infectious diseases
DM Klinman, S Klaschik, T Sato, D Tross - Advanced drug delivery reviews, 2009 - Elsevier
Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs act as immune
adjuvants, accelerating and boosting antigen-specific immune responses. CpG motifs …
adjuvants, accelerating and boosting antigen-specific immune responses. CpG motifs …
Adjuvant properties of CpG oligonucleotides in primates
D Verthelyi - DNA Vaccines: Methods and Protocols, 2006 - Springer
Unlike mammalian DNA, bacterial, plasmid, and synthetic DNA containing unmethylated
CpG dinucleotides in specific sequence contexts are recognized by the Toll-like receptor 9 …
CpG dinucleotides in specific sequence contexts are recognized by the Toll-like receptor 9 …
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