Splenic dependence of the antibody response to thymus‐independent (TI‐2) antigens

PL Amlot, D Grennan… - European journal of …, 1985 - Wiley Online Library
The murine antibody response to T‐independent (TI)‐2 antigens [2, 4‐dinitrophenyl‐Lys‐
Ficoll (DNP‐FIC) and DNP‐hydroxyethyl starch (HES)] was impaired long after splenectomy …

CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE: VII. REQUIREMENT FOR DIFFERENTIATION OF THYMUS-DERIVED CELLS

J Miller, J Sprent, A Basten, NL Warner… - The Journal of …, 1971 - rupress.org
Experiments were designed to test the possibility that thymus-derived (T) cells cooperate
with nonthymus derived (B) cells in antibody responses by acting as passive carriers of …

Splenic macrophages: antigen presenting cells for T1–2 antigens

JH Humphrey - Immunology letters, 1985 - Elsevier
Thymus-independent antigens type 2 (T1–2) such as DNP-Ficoll or DNP-hydroxyethyl starch
are selectively retained in mice and rats by a distinct population of macrophages in the …

Studies of Antibody Formation in Vitro and in Lethally Irradiated Reconstituted Mice: Evidence for an Inhibitory Function of Thymus‐Derived Cells

D Eidinger, H Pross - Scandinavian Journal of Immunology, 1972 - Wiley Online Library
The reconstitutive capacity of normal lymphoid cells versus cells obtained from mice
immunized with keyhole limpet haemocyanin was studied in lethally irradiated syngeneic …

Differences in the recruitment of virgin B cells into antibody responses to thymus‐dependent and thymus‐independent type‐2 antigens

PJL Lane, D Gray, S Oldfield… - European journal of …, 1986 - Wiley Online Library
The bone marrow of mammals generate large numbers of B cells throughout life. Most of
these have a short life span. The subject of this report is to investigate the extent to which …

A requirement for nonspecific T cell factors in antibody responses to" T cell independent" antigens.

RO Endres, E Kushnir, JW Kappler… - … (Baltimore, Md.: 1950 …, 1983 - journals.aai.org
Using murine splenic B cell preparations depleted of macrophages and rigorously depleted
of T cells, we studied the role of nonspecific helper factors in in vitro antibody responses to T …

Complement‐mediated follicular localization of T‐independent type‐2 antigens: the role of marginal zone macrophages revisited

AJM van den Eertwegh, JD Laman… - European journal of …, 1992 - Wiley Online Library
In this study we demonstrate a hitherto undescribed phenomenon, namely that thymus‐
independent type‐2 antigens (TI‐2 Ag) localize in splenic follicles within 1 h after …

Evidence for mouse Th1-and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation.

H Bass, T Mosmann, S Strober - The Journal of experimental medicine, 1989 - rupress.org
Purified CD4+ BALB/c spleen T cells obtained 4-6 wk after total lymphoid irradiation (TLI)
helped normal syngeneic B cells to produce a vigorous antibody response to TNP keyhole …

Regulation of the class of immune response induced by antigen: I. Specific T cells switch the in vivo response from a cell-mediated to humoral mode

PA Bretscher - Cellular immunology, 1983 - Elsevier
Unprimed murine spleen cells, when administered intravenously to irradiated recipients
together with antigen for 7 days, are induced to display either DTH reactivity or to mount a …

[引用][C] Specific Inactivation of Thymus-derived (T) and Non-thymus-derived (B) Lymphocytes by 125I-labelled Antigen

A Basten, J Miller, NL Warner, J Pye - Nature New Biology, 1971 - nature.com
* Phillips, CA, Melnick, JL, and Grim, CA, Proc. Soc. Exp. Page 1 104 * Phillips, CA, Melnick, JL,
and Grim, CA, Amer. J. Epidem., 87, 447 (1968). * Phillips, CA, Melnick, JL, and Grim, CA, Proc …