The real site of action (Angriffspunkt) of drugs is unknown but it is certain, that each drug
before being able to exert an action must enter into a chemical or physico-chemical reaction …

It may be assumed, as pointed out in the preceding paper, that every drug, before acting,
must be adsorbed by dominant receptors, present at the sites of action of the drug. If this is …

It is common practice to interpret the effect of a given drug on a given effector system in
terms of an interaction between the drug and a specific receptive substance or receptor of …

The only way of thinking about drug actions in chemical terms is to consider how the drug
molecule alters the chemical properties or interferes with the biochemical reactions ofliving …

A drug may be defined as a chemical compound which modifies the properties of living cells.
The result of the action of a drug may be observed on single cells, isolated tissues, or whole …

The major premise of this review is that isolated more effective therapeutic agents for man. In
this contissues can be used efıctively to obtain information text, the bias of this paper will be …

THE pharmacological knowledge which has led to, and to some extent defined, the idea of
the drug receptor can be arranged in three parts, concerned with (a) structure-action …

Much has been written about the quantitative aspects of drug antagonism and many
attempts have been made to account for the facts in terms of the generally accepted theory …

The role that sensory nerve endings can play in drug action and the strategy used for its
experimental analysis and proof is first exemplified by three effects of nicotine which are …

T HE effect induced by a drug is the resultant of the interaction between the molecules of the
drug and the molecules of which the biological object is composed. The higher the …