ING5 inhibits migration and invasion of esophageal cancer cells by downregulating the IL-6/CXCL12 signaling pathway
Y Wang, J Tan, J Li, H Chen… - Technology in Cancer …, 2021 - journals.sagepub.com
Esophageal squamous cell carcinoma (ESCC) is a common cancer in East Asia and in other
parts of the world and exhibits a poor prognosis. Growth inhibitor 5 (ING5) is a new member …
parts of the world and exhibits a poor prognosis. Growth inhibitor 5 (ING5) is a new member …
ING5 inhibits cell proliferation and invasion in esophageal squamous cell carcinoma through regulation of the Akt/NF-κB/MMP-9 signaling pathway
GJ Zhang, J Zhao, ML Jiang, LC Zhang - Biochemical and biophysical …, 2018 - Elsevier
The inhibitor of growth 5 (ING5) is a new candidate tumor suppressor gene (TSG) of the ING
family. So far, there have been many reports about its functions related to cancer …
family. So far, there have been many reports about its functions related to cancer …
[HTML][HTML] ING5 knockdown enhances migration and invasion of lung cancer cells by inducing EMT via EGFR/PI3K/Akt and IL-6/STAT3 signaling pathways
XL Liu, XT Zhang, J Meng, HF Zhang, Y Zhao, C Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
ING5 belongs to the Inhibitor of Growth (ING) candidate tumor suppressor family, whose
functions have been involved in the regulation of chromatin remodeling, cell cycle …
functions have been involved in the regulation of chromatin remodeling, cell cycle …
[HTML][HTML] ING5 inhibits cancer aggressiveness via preventing EMT and is a potential prognostic biomarker for lung cancer
F Zhang, X Zhang, J Meng, Y Zhao, X Liu, Y Liu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The proteins of the Inhibitor of Growth (ING) candidate tumor suppressor family are involved
in multiple cellular functions such as cell cycle regulation, apoptosis, and chromatin …
in multiple cellular functions such as cell cycle regulation, apoptosis, and chromatin …
[HTML][HTML] ING5 suppresses proliferation, apoptosis, migration and invasion, and induces autophagy and differentiation of gastric cancer cells: a good marker for …
W Gou, D Shen, X Yang, S Zhao, Y Liu, H Sun, R Su… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Here, we found that ING5 overexpression increased autophagy, differentiation, and
decreased proliferation, apoptosis, migration, invasion and lamellipodia formation in gastric …
decreased proliferation, apoptosis, migration, invasion and lamellipodia formation in gastric …
Tumor suppressor ING4 overexpression contributes to proliferation and invasion inhibition in gastric carcinoma by suppressing the NF-κB signaling pathway
S Li, T Fan, H Liu, J Chen, C Qin, X Ren - Molecular biology reports, 2013 - Springer
There is growing evidence that inhibitor of growth 4 (ING4) plays a pivotal role in
development and progression of multiple different tumors; however, its precise function in …
development and progression of multiple different tumors; however, its precise function in …
[HTML][HTML] Transcriptional regulation of ING5 and its suppressive effects on gastric cancer
H Zheng, H Xue, X Wu, H Xu, E Zhao, Z Cui - Frontiers in Oncology, 2022 - frontiersin.org
ING5 targets histone acetyltransferase or histone deacetylase complexes for local chromatin
remodeling. Its transcriptional regulation and suppressive effects on gastric cancer remain …
remodeling. Its transcriptional regulation and suppressive effects on gastric cancer remain …
[HTML][HTML] The down-regulated ING5 expression in lung cancer: a potential target of gene therapy
S Zhao, X Yang, D Shen, Y Gao, S Shi, J Wu, H Liu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
ING5 can interact with p53, thereby inhibiting cell growth and inducing apoptosis. We found
that ING5 overexpression not only inhibited proliferation, migration, and invasion, but also …
that ING5 overexpression not only inhibited proliferation, migration, and invasion, but also …
[HTML][HTML] The roles of ING5 in gliomas: a good marker for tumorigenesis and a potential target for gene therapy
S Zhao, ZJ Zhao, HY He, JC Wu, XQ Ding, L Yang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
To elucidate the anti-tumor effects and molecular mechanisms of ING5 on glioma cells, we
overexpressed it in U87 cells, and examined the phenotypes and their relevant molecules. It …
overexpressed it in U87 cells, and examined the phenotypes and their relevant molecules. It …
[HTML][HTML] Overexpression of ING5 inhibits HGF-induced proliferation, invasion and EMT in thyroid cancer cells via regulation of the c-Met/PI3K/Akt signaling pathway
W Gao, J Han - Biomedicine & Pharmacotherapy, 2018 - Elsevier
The inhibitor of growth 5 (ING5), a novel member of the ING family, is involved in diverse
biological processes such as cell growth, apoptosis and DNA repair. Recently, ING5 has …
biological processes such as cell growth, apoptosis and DNA repair. Recently, ING5 has …