Radiation-induced lymphomagenesis and leukemogenesis are complex processes
involving both genetic and epigenetic changes. Although genetic alterations during radiation …

Radiation is a well-known genotoxic agent and human carcinogen that gives rise to a variety
of long-term effects. Its detrimental influence on cellular function is actively studied …

DNA methylation is crucial for normal development, proliferation, and proper maintenance of
genome stability for a given organism. A variety of DNA damaging agents that are known to …

Thymus, an important component of hematopoietic tissue, is a well-documented “target” of
radiation carcinogenesis. Both acute and fractionated irradiation result in a high risk of …

Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and
epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) …

It has been acknowledged for many years that radiation exposure induces delayed, non-
targeted effects in the progeny of the irradiated cell. Evidence is beginning to demonstrate …

The effects of ionizing radiation on DNA methylation are of importance due to the role that
DNA methylation plays in maintaining genome stability, and the presence of aberrant DNA …

The biological and genetic effects of chronic low-dose radiation (LDR) exposure and its
relationship to carcinogenesis have received a lot of attention in the recent years. For …

DNA methylation can regulate gene expression and has been shown to modulate cancer
cell biology and chemotherapy resistance. Therapeutic radiation results in a biological …

An understanding of cellular processes that determine the response to ionizing radiation (IR)
exposure is essential to improve radiotherapy and to assess risks to human health after …