Abstract The (2E)-1-(4-Aminophenyl)-3-(3, 4, 5-trimethoxyphenyl)-2-propen-1-one was
prepared by the reaction between 4-aminoacetophenone and 3, 4, 5, trimethoxy …

Background: Cancer is a devastating disease. Many studies have shown that the primary
causes of the aggressive and resistant types of cancer are the overexpression of receptors …

In this study, 2-benzylidene-1-indanone and its derivatives, which is a chalcone compound
and contains indanone in its structure, were examined. Quantum chemical parameters for …

In the present investigation, few 3-(substitutedphenyl)-1-[2-(1-hydroxy-ethyl)]-1H-
benzimidazol-1-yl) prop-2-en-1-ones are EGFR antagonist are designed, by molecular …

Abstract A derivative of naphthaquinone, 2-((1, 5-dimethyl-3-oxo-2-phenyl-2, 3-dihydro-1H-
pyrazol-4-yl) amino) naphthalene-1, 4-dione (DPDHN) was synthesized from lawsone by …

Worldwide cancer is the most prevalent disease which causes severe health problems and
excruciating side effects produced by chemotherapy and radiation-like treatment …

Epidermal growth factor receptors (EGFR) are critical for the growth of many tumors and
expressed at high levels in about one third of epithelial cancers. Hence, blockade of the …

A series of chalcone-based 4-Nitroacetophenone derivatives were designed and
synthesized by the single-step condensation method. These compounds were identified by …

In silico study was performed to twelve 1, 5-benzothiazepine chalcone derivatives with the
protein target from the crystallographic structure modeling of the enzyme tyrosine kinase …

Background: The studies on the potential usage of benzene sulfonamide derivatives as
anticancer agents are limited. benzene sulfonamide derivatives are currently used as …