Clinical application of SNP array analysis in first‐trimester pregnancy loss: A prospective study

Y Wang, Q Cheng, L Meng, C Luo, H Hu… - Clinical …, 2017 - Wiley Online Library
Chromosomal microarray analysis (CMA) has been used routinely in pediatric and prenatal
genetic diagnosis in clinical practice, but it has rarely been applied to miscarriage analysis …

Genomic imbalance in products of conception: single-nucleotide polymorphism chromosomal microarray analysis

B Levy, S Sigurjonsson, B Pettersen… - Obstetrics & …, 2014 - journals.lww.com
OBJECTIVE: To report the full cohort of identifiable anomalies, regardless of known clinical
significance, in a large-scale cohort of postmiscarriage products-of-conception samples …

Application of chromosomal microarray analysis in products of miscarriage

X Zhu, J Li, Y Zhu, W Wang, X Wu, Y Yang, L Gu… - Molecular …, 2018 - Springer
Background Chromosomal abnormality is one of the major cause of spontaneous abortion.
Most available guidelines suggest genetic testing after three miscarriages, which has been …

Chromosomal microarray analysis in pregnancy loss: Is it time for a consensus approach?

SLP Schilit, C Studwell, P Flatley… - Prenatal …, 2022 - Wiley Online Library
Objective To investigate the efficacy and outcomes of chromosomal microarray (CMA) in the
cytogenomic evaluation of products of conception (POC). Method Over a 42‐month period …

[HTML][HTML] Comprehensive genetic analysis of pregnancy loss by chromosomal microarrays: outcomes, benefits, and challenges

T Sahoo, N Dzidic, MN Strecker, S Commander… - Genetics in …, 2017 - Elsevier
Purpose Chromosomal microarray analysis (CMA) is currently considered first-tier testing in
pediatric care and prenatal diagnosis owing to its high diagnostic sensitivity for …

Prenatal chromosomal microarray analysis in a diagnostic laboratory; experience with> 1000 cases and review of the literature

A Breman, AN Pursley, P Hixson, W Bi… - Prenatal …, 2012 - Wiley Online Library
Objective To evaluate the results of prenatal chromosomal microarray analysis (CMA) on>
1000 fetal samples referred for testing at our institution and to compare these data to …

Genetic analysis of first‐trimester miscarriages with a combination of cytogenetic karyotyping, microsatellite genotyping and arrayCGH

YX Zhang, YP Zhang, Y Gu, FJ Guan, SL Li… - Clinical …, 2009 - Wiley Online Library
Miscarriage is the spontaneous loss of an embryo or fetus before the 20th week of
pregnancy. Most miscarriages occur before the end of the first trimester (< 13 weeks) …

Diagnostic utility of microarray testing in pregnancy loss

JA Rosenfeld, ME Tucker, LF Escobar… - … in Obstetrics & …, 2015 - Wiley Online Library
Objectives To determine the frequency of clinically significant chromosomal abnormalities
identified by chromosomal microarray in pregnancy losses at any gestational age and to …

Prenatal diagnosis by chromosomal microarray analysis

B Levy, R Wapner - Fertility and sterility, 2018 - Elsevier
Chromosomal microarray analysis (CMA) is performed either by array comparative genomic
hybridization or by using a single nucleotide polymorphism array. In the prenatal setting …

Chromosomal microarray analysis and prenatal diagnosis

JO Lo, BL Shaffer, CD Feist… - … & gynecological survey, 2014 - journals.lww.com
Chromosomal microarray analysis (CMA) assesses chromosomal copy number alterations
and affords higher resolution when compared with standard karyotype. This review provides …