Inteins excise themselves out of precursor proteins by the protein splicing reaction and have
emerged as valuable protein engineering tools in numerous and diverse biotechnological …

Protein trans-splicing by split inteins has many uses in protein production and research.
Splicing proteins with synthetic peptides, which employs atypical split inteins, is particularly …

Protein splicing in trans by split inteins has increasingly become a powerful protein-
engineering tool for protein ligation, both in vivo and in vitro. Over 100 naturally occurring …

Split inteins carry out a naturally occurring process known as protein trans‐splicing, where
two protein fragments bind to form a catalytically competent enzyme, then catalyze their own …

Inteins are internal protein sequences that post-translationally self-excise and splice
together the flanking sequences, the so-called exteins. Natural and engineered inteins have …

Protein trans‐splicing catalyzed by split inteins has increasingly become useful as a protein
engineering tool. We solved the 1.0 Å‐resolution crystal structure of a fused variant from the …

Split inteins are parasitic genetic elements frequently found inserted into reading frames of
essential proteins. Their association and excision restore host protein function through a …

Inteins are protein segments that are capable of enabling the ligation of flanking extein into a
new protein, a process known as protein splicing. Since its discovery, inteins have become …

Inteins catalyze a post-translational modification known as protein splicing, where the intein
removes itself from a precursor protein and concomitantly ligates the flanking protein …

The protein trans-splicing (PTS) activity of naturally split inteins has found widespread use in
chemical biology and biotechnology. However, currently used naturally split inteins suffer …