Rhomboidal Pt (II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy

Y Sun, F Ding, Z Zhou, C Li, M Pu… - Proceedings of the …, 2019 - National Acad Sciences
Fluorescent theranostics probes at the second near-IR region (NIR-II; 1.0–1.7 µm) are in
high demand for precise theranostics that minimize autofluorescence, reduce photon …

A nano-cocktail of an NIR-II emissive fluorophore and organoplatinum (ii) metallacycle for efficient cancer imaging and therapy

F Ding, Z Chen, WY Kim, A Sharma, C Li… - Chemical …, 2019 - pubs.rsc.org
The scarcity of efficient imaging technologies for precise cancer treatment greatly drives the
development of new nanotheranostic based platforms that enable both diagnostic and …

Gold nanorods functionalized by a glutathione response near-infrared fluorescent probe as a promising nanoplatform for fluorescence imaging guided precision …

Y Huang, Q Liu, Y Wang, N He, R Zhao, J Choo… - Nanoscale, 2019 - pubs.rsc.org
Theranostics nanoplatforms offer opportunities for imaging-guided precision therapy and
hold great potential for clinical applications. In most reported works, the imaging unit has a …

Melanin-dot–mediated delivery of metallacycle for NIR-II/photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy

Y Sun, F Ding, Z Chen, R Zhang, C Li… - Proceedings of the …, 2019 - National Acad Sciences
Discrete Pt (II) metallacycles have potential applications in biomedicine. Herein, we
engineered a dual-modal imaging and chemo-photothermal therapeutic nano-agent 1 that …

Rationally designed Ru (ii)-metallacycle chemo-phototheranostic that emits beyond 1000 nm

C Li, Y Xu, L Tu, M Choi, Y Fan, X Chen, JL Sessler… - Chemical …, 2022 - pubs.rsc.org
Ruthenium complexes are emerging as potential complements to platinum drugs. They also
show promise as photo-diagnostic and therapeutic agents. However, most ruthenium …

An NIR Discrete Metallacycle constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for imaging‐guided cancer Radio‐chemotherapy

Y Ding, Z Tong, L Jin, B Ye, J Zhou, Z Sun… - Advanced …, 2022 - Wiley Online Library
To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …

NIR‐II Emissive Ru (II) Metallacycle Assisting Fluorescence Imaging and Cancer Therapy

Y Fan, C Li, S Bai, X Ma, J Yang, X Guan, Y Sun - Small, 2022 - Wiley Online Library
Despite the success of emissive Ruthenium (Ru) agents in biomedicine, problems such as
the visible‐light excitation/emission and single chemo‐or phototherapy modality still hamper …

Construction of emissive ruthenium (II) metallacycle over 1000 nm wavelength for in vivo biomedical applications

Y Xu, C Li, S Lu, Z Wang, S Liu, X Yu, X Li… - Nature …, 2022 - nature.com
Although Ru (II)-based agents are expected to be promising candidates for substituting Pt-
drug, their in vivo biomedical applications are still limited by the short excitation/emission …

A pH-activatable and aniline-substituted photosensitizer for near-infrared cancer theranostics

J Tian, J Zhou, Z Shen, L Ding, JS Yu, H Ju - Chemical Science, 2015 - pubs.rsc.org
This work reports a newly designed pH-activatable and aniline-substituted aza-boron-
dipyrromethene as a trifunctional photosensitizer to achieve highly selective tumor imaging …

In situ nanozyme‐amplified NIR‐II phototheranostics for tumor‐specific imaging and therapy

Z Ma, MF Foda, H Liang, Y Zhao… - Advanced Functional …, 2021 - Wiley Online Library
The discovery of near‐IR‐II (NIR‐II) tumor phototheranostics holds a great promise for use in
nanomedicine on account of its enhanced penetration depth, high spatial resolution, and …