[HTML][HTML] Shikonin protects against D-Galactosamine and lipopolysaccharide-induced acute hepatic injury by inhibiting TLR4 signaling pathway

MX Lin, YX Yi, PP Fang, SS Huang, CW Pan, LX Jin… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Shikonin, a naphthoquinone isolated from the root of medical herb Lithospermum
erythrorhizon, has been reported to have anti-inflammatory effect. However, there is no …

[HTML][HTML] The protective effects of Shikonin on lipopolysaccharide/d-galactosamine-induced acute liver injury via inhibiting MAPK and NF-κB and activating Nrf2/HO-1 …

Y Tian, Z Li, B Shen, L Wu, L Han, Q Zhang, H Feng - RSC advances, 2017 - pubs.rsc.org
Shikonin (SHK) has various biological and pharmacological activities, including anticancer,
antibacterial and anti-inflammation activities. However, the protective effects and mechanism …

Inhibitory effects of nodakenin on inflammation and cell death in lipopolysaccharide-induced liver injury mice

JY Lim, JH Lee, DH Yun, YM Lee, DK Kim - Phytomedicine, 2021 - Elsevier
Background Nodakenin, a coumarin glucoside isolated from the roots of Angelica biserrata,
has been reported to have anti-inflammatory, antibacterial, anticancer effects. However …

Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome …

X Liu, T Wang, X Liu, L Cai, J Qi, P Zhang… - International …, 2016 - Elsevier
Biochanin A, an isoflavone existed in red clover and peanuts, has been reported to possess
a wide spectrum of pharmacological activities, such as anti-inflammatory and antioxidant …

Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways

Z Peng, X Gong, Y Yang, L Huang, Q Zhang… - International …, 2017 - Elsevier
Quercetin is regarded as a potential hepatoprotective agent in the treatment of acute liver
injury. However, the underlying mechanism of how quercetin to protect against …

Bromelain ameliorates D-galactosamine-induced acute liver injury: role of SIRT1/LKB1/AMPK, GSK3β/Nrf2 and NF-κB p65/TNF-α/caspase-8,-9 signalling pathways

MA Didamoony, AM Atwa… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives The present research focused on estimating, for the first time, the potential
protective effects of bromelain against D-galactosamine-induced acute liver injury in rats as …

[HTML][HTML] Hepatoprotective Effects of Kaempferol-3-O-α-l-Arabinopyranosyl-7-O-α-l-Rhamnopyranoside on d-Galactosamine and Lipopolysaccharide Caused …

L Dong, L Yin, H Quan, Y Chu, J Lu - Molecules, 2017 - mdpi.com
Fulminant hepatic failure (FHF), associated with high mortality, is characterized by extensive
death of hepatocytes and hepatic dysfunction. There is no effective treatment for FHF …

A novel type lavandulyl flavonoid from Sophora flavescens as potential anti-hepatic injury agent that inhibit TLR2/NF-κB signaling pathway

Y Lin, XJ Chen, JJ Li, L He, YR Yang, F Zhong… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacology relevance Sophora flavescens Aiton, was a crucial source of
Traditional Chinese Medicine (TCM) that has benefited human health for hundreds of years …

Flavonoids from Livistona chinensis fruit ameliorates LPS/D-GalN-induced acute liver injury by inhibiting oxidative stress and inflammation

M Wu, C Wang, C Mai, J Chen, X Lai, L He… - Journal of functional …, 2019 - Elsevier
Livistona chinensis fruit is a traditional Chinese medicine widely used for treating hepatitis,
but its protective effect against hepatitis remains unknown. This study investigated the …

[PDF][PDF] Ginkgo biloba extract alleviates CCl4-induced acute liver injury by regulating PI3K/AKT signaling pathway

X Pu, Y Fu, Y Yang, G Xu - Heliyon, 2024 - cell.com
Acute liver injury (ALI) is a global health problem associated with high mortality and has
attracted clinical attention. Ginkgo biloba extract (GBE) is an extract from dried Ginkgo …