Development of exploratory algorithms to aid in risk of malignancy prediction of indeterminate pulmonary nodules

N Jeanblanc, L Jackson, S Gawel, S Brophy… - Clinica Chimica …, 2022 - Elsevier
Early detection of lung cancer allows for earlier stage treatment initiation and improved
patient prognosis. This report focuses on utilization of combining patient demographic …

Improving malignancy risk prediction of indeterminate pulmonary nodules with imaging features and biomarkers

HN Marmor, L Jackson, S Gawel, M Kammer… - Clinica Chimica …, 2022 - Elsevier
Background Non-invasive biomarkers are needed to improve management of indeterminate
pulmonary nodules (IPNs) suspicious for lung cancer. Methods Protein biomarkers were …

Role of biomarkers in lung nodule evaluation

S Sethi, J Cicenia - Current Opinion in Pulmonary Medicine, 2022 - journals.lww.com
Role of biomarkers in lung nodule evaluation : Current Opinion in Pulmonary Medicine Role of
biomarkers in lung nodule evaluation : Current Opinion in Pulmonary Medicine Log in or …

Biomarkers to help guide management of patients with pulmonary nodules

EF Patz Jr, MJ Campa, EB Gottlin… - American journal of …, 2013 - atsjournals.org
Rationale: Indeterminate pulmonary nodules are a common radiographic finding and
require further evaluation because of the concern for lung cancer. Objectives: We developed …

[HTML][HTML] Development and validation of a plasma biomarker panel for discerning clinical significance of indeterminate pulmonary nodules

S Daly, D Rinewalt, C Fhied, S Basu, B Mahon… - Journal of Thoracic …, 2013 - Elsevier
Introduction: The recent findings of the National Lung Screening Trial showed 24.2% of
individuals at high risk for lung cancer having one or more indeterminate nodules detected …

A classifier integrating plasma biomarkers and radiological characteristics for distinguishing malignant from benign pulmonary nodules

Y Lin, Q Leng, Z Jiang, MA Guarnera… - … journal of cancer, 2017 - Wiley Online Library
Lung cancer is primarily caused by cigarette smoking and the leading cancer killer in the
USA and across the world. Early detection of lung cancer by low‐dose CT (LDCT) can …

[HTML][HTML] A prediction model based on biomarkers and clinical characteristics for detection of lung cancer in pulmonary nodules

J Ma, MA Guarnera, W Zhou, HB Fang, F Jiang - Translational oncology, 2017 - Elsevier
Lung cancer early detection by low-dose computed tomography (LDCT) can reduce the
mortality. However, LDCT increases the number of indeterminate pulmonary nodules (PNs) …

[HTML][HTML] Clinical validation of a blood-based classifier for diagnostic evaluation of asymptomatic individuals with pulmonary nodules

CE Birse, JL Tomic, HI Pass, WN Rom, RJ Lagier - Clinical Proteomics, 2017 - Springer
Background The number of pulmonary nodules detected in the US is expected to increase
substantially following recent recommendations for nationwide CT-based lung cancer …

[HTML][HTML] Risk assessment for indeterminate pulmonary nodules using a novel, plasma-protein based biomarker assay

NN Trivedi, M Arjomandi, JK Brown… - … research and clinical …, 2018 - ncbi.nlm.nih.gov
Background: The increase in lung cancer screening is intensifying the need for a
noninvasive test to characterize the many indeterminate pulmonary nodules (IPN) …

[HTML][HTML] Contribution of a blood-based protein biomarker panel to the classification of indeterminate pulmonary nodules

EJ Ostrin, LE Bantis, DO Wilson, N Patel… - Journal of Thoracic …, 2021 - Elsevier
Rationale The workup and longitudinal monitoring for subjects presenting with pulmonary
nodules is a pressing clinical problem. A blood-based biomarker panel potentially has utility …