Diagnostic value of aquaporin-4-IgG live cell based assay in neuromyelitis optica spectrum disorders

V Redenbaugh, M Montalvo, E Sechi… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Objective Determine the utility of aquaporin 4 IgG (AQP4-IgG) testing (live cell-based assay)
for Neuromyelitis Optica Spectrum Disorders (NMOSD). Methods We included Mayo Clinic …

[PDF][PDF] Large-scale in-house cell-based assay for evaluating the serostatus in patients with neuromyelitis optica spectrum disorder based on new diagnostic criteria

Y Kim, G Kim, BS Kong, JE Lee… - Journal of Clinical …, 2017 - synapse.koreamed.org
Background and Purpose The detection of aquaporin 4-IgG (AQP4-IgG) is now a critical
diagnostic criterion for neuromyelitis optica spectrum disorder (NMOSD). To evaluate the …

Clinical usefulness of cell-based indirect immunofluorescence assay for the detection of aquaporin-4 antibodies in neuromyelitis optica spectrum disorder

E Kang, JH Min, KH Lee, BJ Kim - Annals of laboratory …, 2012 - synapse.koreamed.org
Background The presence of antibodies to aquaporin-4 (AQP4) has been identified as a key
characteristic of neuromyelitis optica spectrum disorder (NMOSD), an autoimmune …

Rapid immunodot AQP4 assay for neuromyelitis optica spectrum disorder

Y Fu, J Bi, Y Yan, X Sun, K Li, SY Kim, SM Han… - JAMA …, 2023 - jamanetwork.com
Importance Immunoglobulin G autoantibodies for aquaporin 4 (AQP4-IgG) serve as
diagnostic biomarkers for neuromyelitis optica spectrum disorder (NMOSD), and the most …

Serum aquaporin 4-immunoglobulin G titer and neuromyelitis optica spectrum disorder activity and severity: a systematic review and meta-analysis

J Liu, G Tan, B Li, J Zhang, Y Gao, Y Cao, Z Jia… - Frontiers in …, 2021 - frontiersin.org
Background: Aquaporin 4-immunoglobulin G (AQP4-IgG) plays a major role in the
pathogenesis of neuromyelitis optica spectrum disorder (NMOSD). Seropositive status for …

AQP4 antibody assay sensitivity comparison in the era of the 2015 diagnostic criteria for NMOSD

K Prain, M Woodhall, A Vincent, S Ramanathan… - Frontiers in …, 2019 - frontiersin.org
We have compared five different assays for antibodies to aquaporin-4 in 181 cases of
suspected Neuromyelitis optica spectrum disorders (NMOSD) and 253 controls to assess …

Repeated follow-up of AQP4-IgG titer by cell-based assay in neuromyelitis optica spectrum disorders (NMOSD)

T Akaishi, T Takahashi, I Nakashima, M Abe… - Journal of the …, 2020 - Elsevier
Introduction Neuromyelitis optica spectrum disorder (NMOSD) is characterized by the
presence of serum anti-aquaporin 4 (AQP4) antibody. However, the significance of changes …

Overcoming the challenges in diagnosis of AQP4-IgG positive neuromyelitis optica spectrum disorders in resource poor settings using an indigenized and cost …

L Pandit, C Malli, A D'Cunha, A Sudhir - Journal of Neuroimmunology, 2021 - Elsevier
Background Diagnosis of neuromyelitis optica spectrum disorders (NMOSD) in India is
hindered by limited access to cost effective and sensitive assays for detection of aquaporin-4 …

Anti-aquaporin-4 titer is not predictive of disease course in neuromyelitis optica spectrum disorder: a multicenter cohort study

RA Kessler, MA Mealy, JA Jimenez-Arango… - Multiple sclerosis and …, 2017 - Elsevier
Background Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune
disease associated with a serological antibody to aquaporin-4 (AQP4) detectable in up to …

Anti-aquaporin 4 IgG is not associated with any clinical disease characteristics in neuromyelitis optica spectrum disorder

O Schmetzer, E Lakin, B Roediger, A Duchow… - Frontiers in …, 2021 - frontiersin.org
Background: Neuromyelitis optica spectrum disorder (NMOSD) is a clinically defined,
inflammatory central nervous system (CNS) disease of unknown cause, associated with …